ArticleWorld journal of hepatology2021
Papaya improves non-alcoholic fatty liver disease in obese rats by attenuating oxidative stress, inflammation and lipogenic gene expression.
Article in World journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Therapeutic potential of3 Biotech · 2025Article
- Supplementation of papaya leaf juice has beneficial effects on glucose homeostasis in high fat/high sugar-induced obese and prediabetic adult mice.BMC complementary medicine and therapies · 2024Article
- Coral calcium carried hydrogen ameliorates the severity of non-alcoholic steatohepatitis induced by a choline deficient high carbohydrate fat-free diet in elderly rats.Scientific reports · 2023Article
- Hypoglycemic Potential ofToxics · 2023Article
- Application of herbs and active ingredients ameliorate non-alcoholic fatty liver disease under the guidance of traditional Chinese medicine.Frontiers in endocrinology · 2022Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundNon-alcoholic fatty liver disease (NAFLD) is a global health issue that is correlated with obesity and oxidative stress.
aimTo evaluate the anti-NAFLD effect of papaya in high fat diet induced obesity in rats.
methodsFour-week-old male Sprague-Dawley rats were divided into four groups after 1 wk of acclimatization: Group 1 was the rats fed a normal diet (C); group 2 was the rats fed a high fat diet (HFD); group 3 was the rats fed a HFD with 0.5 mL of papaya juice/100 g body weight (HFL), and group 4 was the rats fed a HFD with 1 mL of papaya juice/100 g body weight (HFH) for 12 wk. At the end of the treatment, blood and tissue samples were collected for biochemical analyses and histological assessment.
resultsThe results of the HFH group showed significantly reduced body weight (HFH
conclusionThese current results provide experimental-based evidence suggesting papaya is an efficacious medicinal fruit for use in the prevention or treatment of NAFLD.
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