Evidence map›Paper›PMID 33815662›Full record

ArticleOxidative medicine and cellular longevity2021

Exosomal circEhmt1 Released from Hypoxia-Pretreated Pericytes Regulates High Glucose-Induced Microvascular Dysfunction via the NFIA/NLRP3 Pathway.

Lin Ye, Hui Guo, Yuan Wang, Yun Peng, Yongxin Zhang, Shu Li, Meina Yang, Ling Wang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Quercetin alleviates tubulointerstitial inflammation by inhibiting exosomes-mediated crosstalk between tubular epithelial cells and macrophages.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lin Ye *Shenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.ORCID https://orcid.org/0000-0002-0350-3020
Hui Guo *Shenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.
Yuan WangShenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.
Yun PengShenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.
Yongxin ZhangShenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.
Shu LiShenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.
Meina YangShenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.
Ling WangShenzhen Eye Hospital, Shenzhen, 518040 Guangdong, China.ORCID https://orcid.org/0000-0002-6280-0885
Shenzhen University Health Science Center · CNJinan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) is a frequently occurring microvascular complication induced by long-term hyperglycemia. Pericyte-endothelial cell crosstalk is critical for maintaining vascular homeostasis and remodeling; however, the molecular mechanism underlying that crosstalk remains unknown. In this study, we explored the crosstalk that occurs between endothelial cells and pericytes in response to diabetic retinopathy. Pericytes were stimulated with cobalt chloride (CoCl

Indexed as

Signal TransductionAnimalsCell HypoxiaCell SurvivalDown-RegulationEndothelial CellsExosomesGlucoseMiceMicrovesselsNeovascularization, PhysiologicNFI Transcription FactorsNLR Family, Pyrin Domain-Containing 3 ProteinPericytesProtective AgentsRNA, CircularGlucoseNfia protein, mouseNFI Transcription FactorsNLR Family, Pyrin Domain-Containing 3 ProteinProtective AgentsRNA, Circular

Identifiers

PMID33815662
PMCPMC7994074
OpenAlexW3137409769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.