Evidence map›Paper›PMID 33815658›Full record

ArticleOxidative medicine and cellular longevity2021

Experimental Chronic Prostatitis/Chronic Pelvic Pain Syndrome Increases Anxiety-Like Behavior: The Role of Brain Oxidative Stress, Serum Corticosterone, and Hippocampal Parvalbumin-Positive Interneurons.

Nikola Šutulović, Željko Grubač, Sonja Šuvakov, Djurdja Jerotić, Nela Puškaš, Djuro Macut, Aleksandra Rašić-Marković, Tatjana Simić, Olivera Stanojlović, Dragan Hrnčić

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  4. Carbon Monoxide in an Experimental Model of Chronic Pelvic Pain Syndrome: The Effects of CORM-A1 on Pain and Anxiety-Related Behaviors.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nikola ŠutulovićInstitute of Medical Physiology "Richard Burian", Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0002-9499-3247
Željko GrubačInstitute of Medical Physiology "Richard Burian", Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0002-0812-2438
Sonja ŠuvakovInstitute of Clinical and Medical Biochemistry, Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0002-3743-1213
Djurdja JerotićInstitute of Clinical and Medical Biochemistry, Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0002-1664-6557
Nela PuškašInstitute of Histology and Embryology "Aleksandar Đ. Kostić", Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0002-5921-974X
Djuro MacutClinic of Endocrinology, Diabetes and Metabolic Disease, CCS, Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0002-6731-8596
Aleksandra Rašić-MarkovićInstitute of Medical Physiology "Richard Burian", Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0003-1131-2328
Tatjana SimićInstitute of Clinical and Medical Biochemistry, Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0001-8683-5129
Olivera StanojlovićInstitute of Medical Physiology "Richard Burian", Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0001-5317-3827
Dragan HrnčićInstitute of Medical Physiology "Richard Burian", Belgrade University Faculty of Medicine, 11000 Belgrade, Serbia.ORCID https://orcid.org/0000-0003-0806-444X
University of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanisms of the brain-related comorbidities in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are still largely unknown, although CP/CPPS is one of the major urological problems in middle-aged men, while these neuropsychological incapacities considerably diminish life quality. The objectives of this study were to assess behavioral patterns in rats with CP/CPPS and to determine whether these patterns depend on alterations in the brain oxidative stress, corticosterone, and hippocampal parvalbumin-positive (PV+) interneurons. Adult male

Indexed as

Behavior, AnimalOxidative StressAnimalsAnxietyBrainChronic PainCorticosteroneElevated Plus Maze TestHippocampusInterneuronsMaleMotor ActivityPain ThresholdParvalbuminsPelvic PainProstateCorticosteroneParvalbumins

Identifiers

PMID33815658
PMCPMC7990537
OpenAlexW3134710680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.