Evidence map›Paper›PMID 33815556›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Network Pharmacology Analysis of Traditional Chinese Medicine Formula Shuang Di Shou Zhen Tablets Treating Nonexudative Age-Related Macular Degeneration.

Yue Fang, Xinquan Liu, Jing Su

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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  8. Exploration of the Effect and Mechanism ofDrug design, development and therapy · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yue FangDepartment of Ophthalmology, Longhua Hospital Affiliated Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.ORCID https://orcid.org/0000-0002-2665-5027
Xinquan LiuDepartment of Ophthalmology, Longhua Hospital Affiliated Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.ORCID https://orcid.org/0000-0003-4395-2004
Jing SuDepartment of Ophthalmology, Longhua Hospital Affiliated Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.ORCID https://orcid.org/0000-0001-5389-734X
Shanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the pharmacological mechanism of the treatment of dry age-related macular degeneration (dry AMD) based on a network pharmacological approach of Shuang Di Shou Zhen Tablets (SDSZT) and to provide a new reference for the current lack of effective treatment of dry AMD.

methodsThe main chemical constituents and their targets of

resultsThe main active ingredients of SDSZT for dry AMD treatment are quercetin, kaempferol, luteolin,

conclusionThis study initially reveals the multiconstituent, multitarget, and multipathway mechanism of action of SDSZT in the treatment of dry AMD and provides the basis for the clinical application of SDSZT.

Identifiers

PMID33815556
PMCPMC8012120
OpenAlexW3136268558

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.