Evidence map›Paper›PMID 33815445›Full record

ArticleFrontiers in plant science2021

β-Hexosaminidases Along the Secretory Pathway of

Nicolò Alvisi, Kim van Noort, Sarlita Dwiani, Nathan Geschiere, Octavina Sukarta, Koen Varossieau, Dieu-Linh Nguyen, Richard Strasser, Cornelis H Hokke, Arjen Schots and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Trafficking and localization of Golgi-residentFrontiers in plant science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Nicolò AlvisiLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Kim van NoortLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Sarlita DwianiLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Nathan GeschiereLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Octavina SukartaLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Koen VarossieauLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Dieu-Linh NguyenDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Richard StrasserDepartment of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Cornelis H HokkeDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Arjen SchotsLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Ruud H P WilbersLaboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
Wageningen University & Research · NLLeiden University Medical Center · NLBOKU University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secretions of parasitic worms (helminths) contain a wide collection of immunomodulatory glycoproteins with the potential to treat inflammatory disorders, like autoimmune diseases. Yet, the identification of single molecules that can be developed into novel biopharmaceuticals is hampered by the limited availability of native parasite-derived proteins. Recently, pioneering work has shown that helminth glycoproteins can be produced transiently in

Indexed as

glyco-engineeringLacdiNAcN-glycosylationNicotiana benthamianaβ-hexosaminidases

Identifiers

PMID33815445
PMCPMC8010188
OpenAlexW3136535108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.