Evidence map›Paper›PMID 33815410›Full record

ArticleFrontiers in immunology2021

HLA Alleles B

Jean C Digitale, Perri C Callaway, Maureen Martin, George Nelson, Mathias Viard, John Rek, Emmanuel Arinaitwe, Grant Dorsey, Moses Kamya, Mary Carrington and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  7. Malaria: past, present, and future.Signal transduction and targeted therapy · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Genetic variation that determinesProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Jean C DigitaleDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Perri C CallawayDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Maureen MartinBasic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology, National Cancer Institute, Bethesda, MD, United States.
George NelsonAdvanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Mathias ViardBasic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology, National Cancer Institute, Bethesda, MD, United States.
John RekInfectious Diseases Research Collaboration, Kampala, Uganda.
Emmanuel ArinaitweInfectious Diseases Research Collaboration, Kampala, Uganda.
Grant DorseyDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Moses KamyaInfectious Diseases Research Collaboration, Kampala, Uganda.
Mary CarringtonBasic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology, National Cancer Institute, Bethesda, MD, United States.
Isabel Rodriguez-BarraquerDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Margaret E FeeneyDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.
University of California, San Francisco · USFrederick National Laboratory for Cancer Research · USInfectious Diseases Research Collaboration · UGNational Cancer Institute · US

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY, MOSES Robert KAMYA · 2010 to 2026
$29.3M
Effects of genetic polymorphism in MHC, KIR, and related loci on human diseaseZIABC010791 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CARRINGTON, MARY N. · 2009 to 2025
$18.2M
The role of γδ T cells in fetal and infant immune defense against malariaR01AI093615 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2011 to 2025
$9.1M
Mentoring Translational Researchers for Careers in Pediatric Global HealthK24AI113002 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2014 to 2023
$1.9M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENIAID NIH HHS K24 AI113002NIAID NIH HHS R01 AI093615NIAID NIH HHS U19 AI089674
6 · The paper itself

Abstract

Variation within the HLA locus been shown to play an important role in the susceptibility to and outcomes of numerous infections, but its influence on immunity to

Indexed as

AdultAllelesAntigens, ProtozoanChildChild, PreschoolEpitopes, T-LymphocyteFemaleFollow-Up StudiesGenetic Predisposition to DiseaseGenotyping TechniquesHLA AntigensHLA-C AntigensHumansIncidenceInfantMalaria, FalciparumAntigens, ProtozoanEpitopes, T-LymphocyteHLA AntigensHLA-B53 antigenHLA-C*06:02 antigenHLA-C AntigensHLAimmunogeneticsmalariaMHCPlasmodium falciparum

Identifiers

PMID33815410
PMCPMC8017319
OpenAlexW3139247263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.