Evidence map›Paper›PMID 33815391›Full record

ArticleFrontiers in immunology2021

Resolvin E1 Regulates Th17 Function and T Cell Activation.

Fatma Oner, Carla Alvarez, Wael Yaghmoor, Danielle Stephens, Hatice Hasturk, Erhan Firatli, Alpdogan Kantarci

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Effects of specialized proresolving mediators on gut epithelial barrier in early life.The Journal of pharmacology and experimental therapeutics · 2026
    Article
  6. Lipid metabolism in homeostasis and disease.Signal transduction and targeted therapy · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. The research progress and potential applications ofThe British journal of nutrition · 2025
    Review
  12. Review
  13. Molecular dynamics of inflammation resolution: therapeutic implications.Frontiers in cell and developmental biology · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Gut microbiota and psoriasis: pathogenesis, targeted therapy, and future directions.Frontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Fatma OnerThe Forsyth Institute, Cambridge, MA, United States.
Carla AlvarezThe Forsyth Institute, Cambridge, MA, United States.
Wael YaghmoorThe Forsyth Institute, Cambridge, MA, United States.
Danielle StephensThe Forsyth Institute, Cambridge, MA, United States.
Hatice HasturkThe Forsyth Institute, Cambridge, MA, United States.
Erhan FiratliDepartment of Periodontology, School of Dentistry, Istanbul University, Istanbul, Turkey.
Alpdogan KantarciThe Forsyth Institute, Cambridge, MA, United States.
Istanbul University · TRHarvard University · USUmm al-Qura University · SAUniversity of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resolvin E1 (RvE1) is a specialized pro-resolving lipid mediator derived from eicosapentaenoic acid and plays a critical role in resolving inflammation and tissue homeostasis. T

Indexed as

AnimalsAntigen PresentationCell DifferentiationCell ProliferationDendritic CellsEicosapentaenoic AcidFemaleInflammationInterleukin-17Interleukin-2 Receptor alpha SubunitInterleukin-6Lymphocyte ActivationMaleMiceMice, Inbred BALB CTh17 Cells5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acidEicosapentaenoic AcidIl17a protein, mouseIL2RA protein, humanInterleukin-17Interleukin-2 Receptor alpha SubunitInterleukin-6interleukin-6, mouseTransforming Growth Factor betaresolution of inflammationresolvinRvE1T cell - DC interactionsT helper (T) 17 cells H

Identifiers

PMID33815391
PMCPMC8009993
OpenAlexW3136853733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.