Evidence map›Paper›PMID 33815383›Full record

ArticleFrontiers in immunology2021

New Pathways for the Skin's Stress Response: The Cholinergic Neuropeptide SLURP-1 Can Activate Mast Cells and Alter Cytokine Production in Mice.

Christoph M Ertle, Frank R Rommel, Susanne Tumala, Yasuhiro Moriwaki, Jochen Klein, Johannes Kruse, Uwe Gieler, Eva M J Peters

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Immune functions of the esophagus.The Journal of allergy and clinical immunology · 2026
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  13. Topical Donepezil for Cholinergic Modulation in Chronic Wound Repair.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Christoph M ErtlePsychoneuroimmunology Laboratory, Clinic for Psychosomatic Medicine and Psychotherapy, Justus-Liebig-University Giessen, Giessen, Germany.
Frank R RommelPsychoneuroimmunology Laboratory, Clinic for Psychosomatic Medicine and Psychotherapy, Justus-Liebig-University Giessen, Giessen, Germany.
Susanne TumalaPsychoneuroimmunology Laboratory, Clinic for Psychosomatic Medicine and Psychotherapy, Justus-Liebig-University Giessen, Giessen, Germany.
Yasuhiro MoriwakiDepartment of Pharmacology, Keio University Faculty of Pharmacy, Tokyo, Japan.
Jochen KleinDepartment of Pharmacology, Biocenter N260, Goethe University Frankfurt, Frankfurt, Germany.
Johannes KruseClinic for Psychosomatic Medicine and Psychotherapy, Justus-Liebig-University Giessen, Giessen, Germany.
Uwe GielerDepartment of Dermatology, University Hospital Giessen, Giessen, Germany.
Eva M J PetersPsychoneuroimmunology Laboratory, Clinic for Psychosomatic Medicine and Psychotherapy, Justus-Liebig-University Giessen, Giessen, Germany.
University of Giessen · DECharité - Universitätsmedizin Berlin · DEGoethe University Frankfurt · DEKeio University · JPUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha7 Nicotinic Acetylcholine ReceptorAnimalsAntigens, LyCell DegranulationCholinergic AgentsCytokinesHypoxia-Inducible Factor 1, alpha SubunitInflammationMast CellsMiceMice, KnockoutNerve FibersNeuropeptidesNoiseOxidative StressSkinalpha7 Nicotinic Acetylcholine ReceptorAntigens, LyCholinergic AgentsChrna7 protein, mouseCytokinesHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitNeuropeptidesSLURP-1 protein, mouseUrokinase-Type Plasminogen Activatoralpha7 nicotinic acetylcholine receptorcholinergic systemChrna7 knockouthypoxia inducible factor 1 alphamast cellssecreted Ly-6/uPAR-related protein 1stress

Identifiers

PMID33815383
PMCPMC8012551
OpenAlexW3136530714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.