Evidence map›Paper›PMID 33815379›Full record

ReviewFrontiers in immunology2021

The Integration of Human and Veterinary Studies for Better Understanding and Management of Crimean-Congo Haemorrhagic Fever.

Ciaran Gilbride, Jack Saunders, Hannah Sharpe, Emmanuel Atangana Maze, Georgina Limon, Anna Barbara Ludi, Teresa Lambe, Sandra Belij-Rammerstorfer

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ciaran GilbrideThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Jack SaundersThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Hannah SharpeThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Emmanuel Atangana MazeThe Pirbright Institute, Woking, United Kingdom.
Georgina LimonThe Pirbright Institute, Woking, United Kingdom.
Anna Barbara LudiThe Pirbright Institute, Woking, United Kingdom.
Teresa LambeThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Sandra Belij-RammerstorferThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

Funding

Biotechnology and Biological Sciences Research Council BB/R019991/1Biotechnology and Biological Sciences Research Council BBS/E/I/00007036Department of Health 16/107/06
6 · The paper itself

Abstract

Outbreaks that occur as a result of zoonotic spillover from an animal reservoir continue to highlight the importance of studying the disease interface between species. One Health approaches recognise the interdependence of human and animal health and the environmental interplay. Improving the understanding and prevention of zoonotic diseases may be achieved through greater consideration of these relationships, potentially leading to better health outcomes across species. In this review, special emphasis is given on the emerging and outbreak pathogen Crimean-Congo Haemorrhagic Fever virus (CCHFV) that can cause severe disease in humans. We discuss the efforts undertaken to better understand CCHF and the importance of integrating veterinary and human research for this pathogen. Furthermore, we consider the use of closely related nairoviruses to model human disease caused by CCHFV. We discuss intervention approaches with potential application for managing CCHFV spread, and how this concept may benefit both animal and human health.

Indexed as

AnimalsDisease Models, AnimalDisease ReservoirsHemorrhagic Fever, CrimeanHemorrhagic Fever Virus, Crimean-CongoHumansViral VaccinesViral ZoonosesViral VaccinesCCHFHazaramouse modelNHP modelNSDVOne Healthvaccinesveterinary vaccines

Identifiers

PMID33815379
PMCPMC8012513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.