Evidence map›Paper›PMID 33815374›Full record

ArticleFrontiers in immunology2021

Wenhui Pang, Yan Jiang, Aifeng Li, Jisheng Zhang, Min Chen, Li Hu, Zhiyuan Li, Dehui Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. The Modulatory Effects ofInternational journal of endocrinology and metabolism · 2025
    Article
  13. Article
  14. Article
  15. Microbiology spectrum · 2025
    Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wenhui PangDepartment of Otolaryngology-Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yan JiangDepartment of Otolaryngology-Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Aifeng LiDepartment of Otolaryngology-Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jisheng ZhangMedical Research Center, Key Laboratory of Otolaryngology-Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Min ChenDepartment of Otolaryngology-Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Li HuENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Zhiyuan LiMedical Research Center, Key Laboratory of Otolaryngology-Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Dehui WangENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Qingdao University · CNEye & ENT Hospital of Fudan University · CNAffiliated Hospital of Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibition of allergic airway diseases (AAD) by immunomodulation of the adaptive immune system through restoration of the enteric dysbiosis is an emerging therapeutic strategy. Patients with allergic rhinitis (n = 6) and healthy controls (n = 6) were enrolled, and gut microbiome composition analysis was performed by 16S rDNA sequencing. We also established an ovalbumin (OVA)-induced allergic airway inflammation murine model. Dysbiosis of the gut flora was observed in both AAD patients and the mice, with the decrease of the biodiversity and the quantity of the Bacteroidetes phylum. Oral application of

Indexed as

AllergensAnimalsBacteroides thetaiotaomicronCells, CulturedCytokinesGastrointestinal MicrobiomeHumansHypersensitivityImmunomodulationInducible T-Cell Co-Stimulator ProteinInflammationMiceMice, Inbred BALB CModels, AnimalOvalbuminRespiratory HypersensitivityAllergensCytokinesInducible T-Cell Co-Stimulator ProteinOvalbumin16s rRNA geneallergic airway diseasesBacteroides thetaiotaomicrondysbiosisregulatory T cells

Identifiers

PMID33815374
PMCPMC8010693
OpenAlexW3137338491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.