Evidence map›Paper›PMID 33815351›Full record

ArticleFrontiers in immunology2020

A Real-Time PCR Assay for the Diagnosis of Intestinal Schistosomiasis and Cure Assessment After the Treatment of Individuals With Low Parasite Burden.

Liliane Maria Vidal Siqueira, Carolina Senra, Áureo Almeida de Oliveira, Nidia Francisca de Figueiredo Carneiro, Luciana Inácia Gomes, Ana Rabello, Paulo Marcos Zech Coelho, Edward Oliveira

Open access · goldAbstract readComparative StudyMulticenter StudyValidation Study
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Liliane Maria Vidal SiqueiraDiagnosis and Therapy of Infectious and Oncologic Diseases, Instituto René Rachou, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Carolina SenraClinical Research and Public Politics in Infectious and Parasitic Diseases, Instituto René Rachou, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Áureo Almeida de OliveiraDiagnosis and Therapy of Infectious and Oncologic Diseases, Instituto René Rachou, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Nidia Francisca de Figueiredo CarneiroSchool of Medicine, Universidade Estadual de Montes Claros (UNIMONTES), Montes Claros, Brazil.
Luciana Inácia GomesClinical Research and Public Politics in Infectious and Parasitic Diseases, Instituto René Rachou, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Ana RabelloClinical Research and Public Politics in Infectious and Parasitic Diseases, Instituto René Rachou, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Paulo Marcos Zech CoelhoDiagnosis and Therapy of Infectious and Oncologic Diseases, Instituto René Rachou, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Edward OliveiraClinical Research and Public Politics in Infectious and Parasitic Diseases, Instituto René Rachou, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Fundação Oswaldo Cruz · BRUniversidade Estadual de Montes Claros · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The laboratorial diagnosis of the intestinal schistosomiasis is always performed using Kato-Katz technique. However, this technique presents low sensitivity for diagnosis of individuals with low parasite burden, which constitutes the majority in low endemicity Brazilian locations for the disease. The objective of this study was developed and to validate a real-time PCR assay (qPCR) targeting 121 bp sequence to detect

Indexed as

AdolescentAdultAgedAged, 80 and overAnimalsAnthelminticsChildChild, PreschoolCross-Sectional StudiesDNA, HelminthFecesFemaleHelminthsHumansInfantMaleAnthelminticsDNA, HelminthOligodeoxyribonucleotidesPraziquantelintestinal schistosomiasisKato–Katz techniquelaboratory diagnosisreal-time PCRsaline gradient technique

Identifiers

PMID33815351
PMCPMC8010660
OpenAlexW3137428572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.