ArticleFrontiers in endocrinology2021
Insulin Action, Glucose Homeostasis and Free Fatty Acid Metabolism: Insights From a Novel Model.
Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Understanding Insulin Actions Beyond Glycemic Control: A Narrative Review.Journal of clinical medicine · 2025Review
- Changes in Lipid Metabolism under Alloxan Diabetes in Laboratory Animals and the Influence of Antidiabetic and Hypoglycemic Therapy on These Changes.Bulletin of experimental biology and medicine · 2025Article
- GLP-1 and Its Role in Glycogen Production: A Narrative Review.Biomedicines · 2025Review
- The impact of hyperinsulinemia on short-term prognosis in patients with hypertriglyceridemia-induced acute pancreatitis.Frontiers in endocrinology · 2025Article
- Molecular Links and Clinical Effects of Inflammation and Metabolic Background on Ischemic Stroke: An Update Review.Journal of clinical medicine · 2024Review
- The U -shape relationship between free fatty acid level and adverse outcomes in coronary artery disease patients with hypertension: evidence from a large prospective cohort study.Lipids in health and disease · 2024Article
- Model selection reveals selective regulation of blood amino acid and lipid metabolism by insulin in humans.iScience · 2024Article
- Preoperative contributing factors and the remission of diabetes after metabolic surgery: the mediating role of preoperative triglyceride.Eating and weight disorders : EWD · 2024Article
- A new oral model of free fatty acid kinetics to assess lipolysis in subjects with and without type 2 diabetes.American journal of physiology. Endocrinology and metabolism · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glucose and free fatty acids (FFA) are essential nutrients that are both partly regulated by insulin. Impaired insulin secretion and insulin resistance are hallmarks of aberrant glucose disposal, and type 2 diabetes (T2DM). In the current study, a novel model of FFA kinetics is proposed to estimate the role insulin action on FFA lipolysis and oxidation allowing estimation of adipose tissue insulin sensitivity (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.