ArticleFrontiers in physiology2021
Clinical Interpretation of Cardiopulmonary Exercise Testing: Current Pitfalls and Limitations.
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Pooled it
- A protocol for validation of novel artificial intelligence-based framework for dyspnoea investigation with cardiopulmonary exercise testing.ERJ open research · 2026Article
- ERS Congress 2025: highlights from the Respiratory Clinical Care and Physiology Assembly.ERJ open research · 2026Article
- Measurement Properties of the Modified Incremental Step Test for Assessing Exercise Capacity in Individuals With Type 2 Diabetes.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Four decades applying clinical physiology to respiratory medicine: a personal account of occasional certainties and perennial doubts.Respiratory research & clinical practice · 2026Article
- Association between fibrinogen and decline in cardiorespiratory fitness in patients undergoing cardiopulmonary exercise testing: a large cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- AI-Techniques Loss-Based Algorithm for Severity Classification (ATLAS): a novel approach for continuous quantification of exertional symptoms during incremental exercise testing.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Assessment of cardiorespiratory fitness and body composition in marathon runners with type 1 diabetes: an observational study.BMC sports science, medicine & rehabilitation · 2025Article
- Cardiopulmonary Exercise Testing in the Prognostic Assessment of Heart Failure: From a Standardized Approach to Tailored Therapeutic Strategies.Medicina (Kaunas, Lithuania) · 2025Review
- Exertional inspiratory capacity and operating lung volumes in health: a population-based study.ERJ open research · 2025Article
- Impact of personalized accurate intensity exercise on radial artery pulse wave in patients with multi-chronic diseases: a holistic functional assessment approach.Journal of thoracic disease · 2025Article
- Ventilatory Response to Exercise in HFrEF-COPD: Importance of Exercise Modality.Journal of clinical medicine · 2025Article
- Management and Medical Care for Individuals with Type 1 Diabetes Running a Marathon.Journal of clinical medicine · 2025Article
- Abbreviated Duke Activity Status Index for Risk Stratification in Heart Failure.The American journal of cardiology · 2025Article
- Oxygen uptake efficiency slope at anaerobic threshold can predict peak VOInternational journal of cardiology. Congenital heart disease · 2024Article
- Cardiopulmonary Exercise Testing: Methodology, Interpretation, and Role in Exercise Prescription for Cardiac Rehabilitation.US cardiology · 2024Review
- Functional Data Analysis for Predicting Pediatric Failure to Complete Ten Brief Exercise Bouts.IEEE journal of biomedical and health informatics · 2022Article
- Heart rate and gas exchange dynamic responses to multiple brief exercise bouts (MBEB) in early- and late-pubertal boys and girls.Physiological reports · 2022Article
- Pathophysiology and clinical evaluation of the patient with unexplained persistent dyspnea.Expert review of respiratory medicine · 2022Review
- Respiratory Activity during Exercise: A Feasibility Study on Transition Point Estimation Using Impedance Pneumography.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several shortcomings on cardiopulmonary exercise testing (CPET) interpretation have shed a negative light on the test as a clinically useful tool. For instance, the reader should recognize patterns of dysfunction based on clusters of variables rather than relying on rigid interpretative algorithms. Correct display of key graphical data is of foremost relevance: prolixity and redundancy should be avoided. Submaximal dyspnea ratings should be plotted as a function of work rate (WR) and ventilatory demand. Increased work of breathing and/or obesity may normalize peak oxygen uptake (V̇O
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.