Evidence map›Paper›PMID 33815110›Full record

ArticleFrontiers in pharmacology2021

Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage.

Lining Duan, Ying Zhang, Yuna Yang, Shiyu Su, Ligui Zhou, Po-Chieh Lo, Jiaying Cai, Yiqi Qiao, Min Li, Shuiqing Huang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Pooled it
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  14. Baicalin plays a protective role by regulating ferroptosis in multiple diseases.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Lining DuanScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Ying ZhangScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yuna YangScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Shiyu SuScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Ligui ZhouScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Po-Chieh LoScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jiaying CaiScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yiqi QiaoScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Min LiScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Shuiqing HuangScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Hong WangScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yousheng MoScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qi WangScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracerebral hemorrhage (ICH) is a subtype of stroke characterized by high mortality and disability rates. To date, the exact etiology of ICH-induced brain injury is still unclear. Moreover, there is no effective treatment to delay or prevent disease progression currently. Increasing evidence suggests that ferroptosis plays a dominant role in the pathogenesis of ICH injury. Baicalin is a main active ingredient of Chinese herbal medicine

Indexed as

baicalinChinese herbal medicineferroptosisheminintracerebral hemorrhage

Identifiers

PMID33815110
PMCPMC8017143
OpenAlexW3138215645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.