ArticleFrontiers in systems neuroscience2021
Laminar Profile of Auditory Steady-State Response in the Auditory Cortex of Awake Mice.
Article in Frontiers in systems neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 10 citations in OpenAlex.
- The clinical analysis of 3 patients diagnosed with sporadic Creutzfeldt-Jakob disease: A case report.Medicine · 2026Article
- The Application of Gamma-Range Auditory Steady-State Responses in Animal Models: A Semi-Structured Literature Review.Brain sciences · 2025Review
- Common Genomic and Proteomic Alterations Related to Disturbed Neural Oscillatory Activity in Schizophrenia.International journal of molecular sciences · 2025Review
- Cortical layer-specific abnormalities in auditory responses in a mouse model of Fragile X Syndrome.Neurobiology of disease · 2025Article
- DX243 counteracts both acoustic trauma-induced reduction in cortical brain oscillations and cochlear synaptopathy.Frontiers in pharmacology · 2025Article
- Network resonance and the auditory steady state response.Scientific reports · 2024Article
- The Thalamocortical Mechanism Underlying the Generation and Regulation of the Auditory Steady-State Responses in Awake Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Detecting Central Auditory Processing Disorders in Awake Mice.Brain sciences · 2023Article
- Differential Effects of Clozapine and Haloperidol on the 40 Hz Auditory Steady State Response-mediated Phase Resetting in the Prefrontal Cortex of the Female Sprague Dawley Rat.Schizophrenia bulletin · 2023Article
- Auditory driven gamma synchrony is associated with cortical thickness in widespread cortical areas.NeuroImage · 2022Article
- Transcranial alternating current stimulation combined with sound stimulation improves cognitive function in patients with Alzheimer's disease: Study protocol for a randomized controlled trial.Frontiers in aging neuroscience · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAuditory steady-state response (ASSR) is a gamma oscillation evoked by periodic auditory stimuli, which is commonly used in clinical electroencephalographic examination to evaluate the neurological functions. Though it has been suggested that auditory cortex is the origin of ASSR, how the laminar architecture of the neocortex contributes to the ASSR recorded from the brain surface remains unclear.
methodsWe used a 16-channel silicon probe to record the local field potential and the single-unit spike activity in the different layers of the auditory cortex of unanesthetized mice. Click-trains with a repetition rate at 40-Hz were present as sound stimuli to evoke ASSR.
resultsWe found that the LFPs of all cortical layers showed a stable ASSR synchronizing to the 40-Hz click stimuli, while the ASSR was strongest in the granular (thalamorecipient) layer. Furthermore, time-frequency analyses also revealed the strongest coherence between the signals recorded from the granular layer and pial surface.
conclusionOur results reveal that the 40-Hz ASSR primarily shows the evoked gamma oscillation of thalamorecipient layers in the neocortex, and that the ASSR may be a biomarker to detect the cognitive deficits associated with impaired thalamo-cortical connection.
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