ArticleFrontiers in molecular neuroscience2021
Tau: A Signaling Hub Protein.
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Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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0cells of the map it votes in
47citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
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Who cites it
47 citing papers in PubMed, 72 citations in OpenAlex.
- Patient-derived forebrain cortical organoids reveal biphasic tau-MAP6-microtubule axis dysfunction in tauopathy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Review
- Impact of Tau overexpression on DNA replication dynamics in centromeres of human neural progenitor cells.iScience · 2026Article
- Tau condensation on DNA mediates microtubule attachment suggesting a mitotic role for centromere-localized tau.Nature communications · 2026Article
- Inhibition of pathogenic tau signaling via blocking of the phosphatase-activating domain by novel small molecules.Frontiers in pharmacology · 2026Article
- Modeling Alzheimer's disease with brain organoids: mechanisms, applications, and future directions.Frontiers in cell and developmental biology · 2026Review
- Pretangle tau pathology accrual in the default mode network during the progression of Alzheimer's disease.Molecular neurodegeneration advances · 2026Article
- Post-translational modifications as a regulatory code for tau function in health and disease.Frontiers in dementia · 2026Review
- Probing tau citrullination in Alzheimer's disease brains and mouse models of tauopathy.Acta neuropathologica · 2025Article
- Histone Deacetylase 2 in Alzheimer's Disease: A Comprehensive Molecular Blueprint for Therapeutic Targeting.Molecular neurobiology · 2025Review
- Tau-Mitochondria Interactions in Neurodegeneration: Mechanisms and Therapeutic Potential.Cellular and molecular neurobiology · 2025Review
- BioID2-Based Tau Interactome Reveals Novel and Known Protein Interactions Associated with Multiple Cellular Pathways.Journal of proteome research · 2025Article
- Tau-Targeted Therapeutic Strategies: Mechanistic Targets, Clinical Pipelines, and Analysis of Failures.Cells · 2025Review
- Bezafibrate treatment rescues neurodevelopmental and neurodegenerative defects in 3D cortical organoid model of MAPT frontotemporal dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics.Proteins · 2025Review
- Polyamination with spermidine enhances pathogenic tau conformations while reducing filamentous aggregate formation in vitro.The Biochemical journal · 2025Article
- Contributions of major tau kinase activation and phospho-tau accumulation to cortical and hippocampal tangle formation and cognition in older adults.Neurobiology of disease · 2025Article
- Neuroplasticity After Hypoxic-Ischemic Brain Injury in Neonatal Pigs Based on Time-Dependent Behavior ofNeurochemical research · 2025Article
- Genetic Insights into Brain Morphology: a Genome-Wide Association Study of Cortical Thickness and TNeuroinformatics · 2025Article
- Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies.ACS pharmacology & translational science · 2025Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Rebecca L MuellerDepartment of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States.
Benjamin CombsDepartment of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States.
Mohammed M AlhadidyDepartment of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States.
Scott T BradyDepartment of Anatomy and Cell Biology, The University of Illinois at Chicago, Chicago, IL, United States.
Gerardo A MorfiniDepartment of Anatomy and Cell Biology, The University of Illinois at Chicago, Chicago, IL, United States.
Nicholas M KanaanDepartment of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States.
Michigan State University · USMarine Biological Laboratory · USMercy Health Saint Mary's · USUniversity of Illinois Chicago · US
Funding
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2016 to 2020
$10.1MTau Conformation in Tauopathies and Neuronal FunctionR01NS082730 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BRADY, SCOTT THOMAS, KANAAN, NICHOLAS M · 2014 to 2023
$7.0MMOLECULAR MECHANISMS OF AXONAL TRANSPORTR01NS023868 · NINDS · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI BRADY, SCOTT THOMAS · 1986 to 2010
$3.7MMechanisms of SPG4 Hereditary Spastic ParaplegiaR01NS118177 · NINDS · DREXEL UNIVERSITY · PI BAAS, PETER W., MORFINI, GERARDO ANDRES · 2020 to 2024
$3.2MTau-Mediated Regulation and Dysregulation of Protein Phosphatase 1R01AG067762 · NIA · MICHIGAN STATE UNIVERSITY · PI KANAAN, NICHOLAS M · 2020 to 2024
$2.6MTau-induced axonal degeneration in Alzheimer's disease and tauopathiesR01AG044372 · NIA · MICHIGAN STATE UNIVERSITY · PI KANAAN, NICHOLAS M · 2014 to 2018
$1.9MREGULATION OF FAST AXONAL TRANSPORT DIABETIC NEUROPATHYR01NS041170 · NINDS · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI BRADY, SCOTT THOMAS · 2000 to 2004
$1.6MIntegrative Training in the Pharmacological SciencesT32GM092715 · NIGMS · MICHIGAN STATE UNIVERSITY · PI NEUBIG, RICHARD R · 2011 to 2020
$1.5MRole of p38alpha signaling in mutant SOD1-linked motor neuron diseaseR21NS120126 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BOSCO, DARYL ANGELA, MORFINI, GERARDO ANDRES · 2020 to 2020
$458kNIA NIH HHS P30 AG053760NIA NIH HHS R01 AG044372NIA NIH HHS R01 AG067762NINDS NIH HHS R01 NS023868NINDS NIH HHS R01 NS041170NINDS NIH HHS R01 NS082730NINDS NIH HHS R01 NS118177NINDS NIH HHS R21 NS120126
Abstract
Over four decades ago,
Indexed as
axonkinasenucleusoligodendrocytephosphatasescaffold proteinsynpasetauopathy
Identifiers
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.