ReviewTopics in spinal cord injury rehabilitation2021
Neurogenic Obesity-Induced Insulin Resistance and Type 2 Diabetes Mellitus in Chronic Spinal Cord Injury.
Review in Topics in spinal cord injury rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- The effects of exercise training on cardiometabolic health in adults with spinal cord injury: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Evaluating the risk of type 2 diabetes mellitus after spinal cord injury: insights from a systematic review and meta-analysis.Spinal cord · 2026Pooled it
- Pooled it
- Prevalence, association, and associated factors of diabetes mellitus in individuals with spinal cord injury: a systematic review and meta-analysis.Spinal cord · 2026Review
- Development and content validity of a nutrition knowledge questionnaire for individuals living with spinal cord injuries and disorders.Spinal cord · 2026Article
- Progress on Omega-3 fatty acids for the comprehensive and targeted treatment of spinal cord injury.Bone research · 2026Review
- Retrospective cohort study of type 2 diabetes effects on chronic wound healing in dermatology clinics.Bioinformation · 2026Article
- Effects of crank length on the cardiovascular response in a rat model of motorized cycling.Spinal cord · 2026Article
- Dysfunction of pancreatic exocrine secretion after experimental spinal cord injury.Experimental neurology · 2025Article
- Article
- Cardiometabolic Risk in Chronic Spinal Cord Injury: A Systematic Review with Meta-Analysis and Temporal and Geographical Trends.Journal of clinical medicine · 2025Review
- Treatment of obesity in spinal cord injury with tirzepatide: a case report.Spinal cord series and cases · 2025Article
- Short-Term and Long-Term Risk of Diabetes Mellitus among Patients with Spinal Cord Injury: A Nationwide Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2024Article
- The Clinical Management of Electrical Stimulation Therapies in the Rehabilitation of Individuals with Spinal Cord Injuries.Journal of clinical medicine · 2024Review
- Physical and emotional consequences of excess weight as experienced by individuals with spinal cord injuries.The journal of spinal cord medicine · 2024Article
- Modification of the Diabetes Prevention Program Lifestyle Intervention in Persons with Spinal Cord Injury: Efficacy for Reducing Major Cardiometabolic Risks, Increased Fitness, and Improved Health-Related Quality of Life.Journal of spine research and surgery · 2024Article
- The Impact of Caregiver/Care-Receiver Co-Treatment in a Therapeutic Lifestyle Intervention for Chronic Spinal Cord Injury: A Comparative Case Series.Annals of case reports · 2024Article
- Effects of vitamin D supplementation on glucose and lipid metabolism in patients with type 2 diabetes mellitus and risk factors for insulin resistance.World journal of diabetes · 2023Article
- Predictors of lower extremity fracture-related amputation in persons with traumatic spinal cord injury: a case-control study.Spinal cord · 2023Article
- Is there any difference in insulin resistance status between cases of benign and malignant ovarian neoplasms? A study on surrogate markers of insulin resistance in Indonesian non-diabetic women.Oncology letters · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The population with SCI is at a significant risk for both insulin resistance and type 2 diabetes mellitus (T2DM) secondary to neurogenic obesity. The prevalence of insulin resistance and T2DM in persons with SCI suggests that disorders of carbohydrate metabolism are at epidemic proportions within the population. However, the true frequency of such disorders may be underestimated because biomarkers of insulin resistance and T2DM used from the population without SCI remain nonspecific and may in fact fail to identify true cases that would benefit from intervention. Furthermore, diet and exercise have been used to help mitigate neurogenic obesity, but results on disorders of carbohydrate metabolism remain inconsistent, likely because of the various ways carbohydrate metabolism is assessed. The objective of this article is to review current literature on the prevalence and likely mechanisms driving insulin resistance and T2DM in persons with SCI. This article also explores the various assessments and diagnostic criteria used for insulin resistance and T2DM and briefly discusses the effects of exercise and/or diet to mitigate disorders of carbohydrate metabolism brought on by neurogenic obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.