ArticleCommunications in nonlinear science & numerical simulation2019
Large time step discrete-time modeling of sharp wave activity in hippocampal area CA3.
Article in Communications in nonlinear science & numerical simulation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Formation and retrieval of cell assemblies in a biologically realistic spiking neural network model of area CA3 in the mouse hippocampus.Journal of computational neuroscience · 2024Article
- Single closed-loop acoustic stimulation targeting memory consolidation suppressed hippocampal ripple and thalamo-cortical spindle activity in mice.The European journal of neuroscience · 2024Article
- Bidirectional Interaction of Hippocampal Ripples and Cortical Slow Waves Leads to Coordinated Spiking Activity During NREM Sleep.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- NMDA receptors promote hippocampal sharp-wave ripples and the associated coactivity of CA1 pyramidal cells.Hippocampus · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Reduced models of neuronal spiking activity simulated with a fixed integration time are frequently used in studies of spatio-temporal dynamics of neurobiological networks. The choice of fixed time step integration provides computational simplicity and efficiency, especially in cases dealing with large number of neurons and synapses operating at a different level of activity across the population at any given time. A network model tuned to generate a particular type of oscillations or wave patterns is sensitive to the intrinsic properties of neurons and synapses and, therefore, commonly susceptible to changes the time step of integration. In this study, we analyzed a model of sharp-wave activity in the network of hippocampal area CA3, to examine how an increase of the integration time step affects network behavior and to propose adjustments of intrinsic properties neurons and synapses that help minimize or remove the damage caused by the time step increase.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.