Evidence map›Paper›PMID 33814733›Full record

ArticleChaos, solitons, and fractals2021

Uncertainty quantification of a mathematical model of COVID-19 transmission dynamics with mass vaccination strategy.

Alberto Olivares, Ernesto Staffetti

Abstract read
In one paragraph

Article in Chaos, solitons, and fractals, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Decoding uncertainty for clinical decision-making.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Projecting the Pandemic Trajectory through Modeling the Transmission Dynamics of COVID-19.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Optimal control-based vaccination and testing strategies for COVID-19.Computer methods and programs in biomedicine · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. A Mathematical Model of COVID-19 with Vaccination and Treatment.Computational and mathematical methods in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alberto OlivaresUniversidad Rey Juan Carlos, Camino del Molino 5, Fuenlabrada 28942, Madrid, Spain.
Ernesto StaffettiUniversidad Rey Juan Carlos, Camino del Molino 5, Fuenlabrada 28942, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, the uncertainty quantification and sensitivity analysis of a mathematical model of the SARS-CoV-2 virus transmission dynamics with mass vaccination strategy has been carried out. More specifically, a compartmental epidemic model has been considered, in which vaccination, social distance measures, and testing of susceptible individuals have been included. Since the application of these mitigation measures entails a degree of uncertainty, the effects of the uncertainty about the application of social distance actions and testing of susceptible individuals on the disease transmission have been quantified, under the assumption of a mass vaccination program deployment. A spectral approach has been employed, which allows the uncertainty propagation through the epidemic model to be represented by means of the polynomial chaos expansion of the output random variables. In particular, a statistical moment-based polynomial chaos expansion has been implemented, which provides a surrogate model for the compartments of the epidemic model, and allows the statistics, the probability distributions of the interesting output variables of the model at a given time instant to be estimated and the sensitivity analysis to be conducted. The purpose of the sensitivity analysis is to understand which uncertain parameters have most influence on a given output random variable of the model at a given time instant. Several numerical experiments have been conducted whose results show that the proposed spectral approach to uncertainty quantification and sensitivity analysis of epidemic models provides a useful tool to control and mitigate the effects of the COVID-19 pandemic, when it comes to healthcare resource planning.

Indexed as

COVID-19 transmission dynamicsMass vaccination strategyMitigation measuresPolynomial chaos expansionSensitivity analysisUncertainty quantification

Identifiers

PMID33814733
PMCPMC7998051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.