Evidence map›Paper›PMID 33814610›Full record

ArticleThe journal of extra-corporeal technology2021

Hematic Antegrade Repriming: A Reproducible Method to Decrease the Cardiopulmonary Bypass Insult.

Juan Blanco-Morillo, José María Arribas-Leal, Piero Farina, Angel Luis Fernández-González, Ángel Sornichero-Caballero, Pablo Ramírez-Romero, Tyler N Chen, Diego Salmerón-Martínez, Sergio Juan Cánovas-López

Abstract read
In one paragraph

Article in The journal of extra-corporeal technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Juan Blanco-MorilloCardiac Surgery Department (SCS), Virgen de la Arrixaca University Hospital, Murcia, Spain.
José María Arribas-LealCardiac Surgery Department (SCS), Virgen de la Arrixaca University Hospital, Murcia, Spain.
Piero FarinaSCS, University Hospital Agostino Gemelli, Rome, Italy.
Angel Luis Fernández-GonzálezSCS Santiago de Compostela University Hospital, Santiago de Compostela, Spain.
Ángel Sornichero-CaballeroCardiac Surgery Department (SCS), Virgen de la Arrixaca University Hospital, Murcia, Spain.
Pablo Ramírez-RomeroHealth Science Research Institute (IMIB), Murcia, Spain.
Tyler N ChenDepartment of Bioengineering, Stanford University, Stanford, California.
Diego Salmerón-MartínezBiostatistics Department, Medicine Faculty, University of Murcia, Murcia, Spain.
Sergio Juan Cánovas-LópezCardiac Surgery Department (SCS), Virgen de la Arrixaca University Hospital, Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current practice of cardiopulmonary bypass (CPB) requires a preoperative priming of the circuit that is frequently performed with crystalloid solutions. Crystalloid priming avoids massive embolism but is unable to eliminate all microbubbles contained in the circuit. In addition, it causes a sudden hemodilution which is correlated with transfusion requirements and an increased risk of cognitive impairment. Several repriming techniques using autologous blood, collectively termed retrograde autologous priming (RAP), have been demonstrated to reduce the hemodilutional impact of CPB. However, the current heterogeneity in the practice of RAP limits its evidence and benefits. Here, we describe hematic antegrade repriming as an easy and reliable method that could be applied with any circuit in the market to decrease transfusion requirements, emboli, and inflammatory responses, reducing costs and the impact of CPB on postoperative recovery.

Indexed as

Blood Transfusion, AutologousCardiopulmonary BypassBlood TransfusionCrystalloid SolutionsHemodilutionHumansCrystalloid Solutionscardiopulmonary bypasshematic priminghemodilutionmicroemboliMiECC

Identifiers

PMID33814610
PMCPMC7995623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.