Evidence map›Paper›PMID 33814495›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Salvage Cord Blood Transplantation for Sustained Remission of Acute Megakaryoblastic Leukemia That Relapsed Early after Myeloablative Transplantation.

Satoshi Ichikawa, Tohru Fujiwara, Kei Saito, Kazuki Sakurai, Kyoko Inokura, Noriko Fukuhara, Hisayuki Yokoyama, Koichi Onodera, Yasushi Onishi, Junichi Kameoka and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Satoshi IchikawaDepartment of Hematology, Tohoku University Hospital, Japan.
Tohru FujiwaraDepartment of Hematology, Tohoku University Hospital, Japan.
Kei SaitoDepartment of Hematology, Tohoku University Hospital, Japan.
Kazuki SakuraiDepartment of Hematology, Tohoku University Hospital, Japan.
Kyoko InokuraDepartment of Hematology, Tohoku University Hospital, Japan.
Noriko FukuharaDepartment of Hematology, Tohoku University Hospital, Japan.
Hisayuki YokoyamaDepartment of Hematology, Tohoku University Hospital, Japan.
Koichi OnoderaDepartment of Hematology, Tohoku University Hospital, Japan.
Yasushi OnishiDepartment of Hematology, Tohoku University Hospital, Japan.
Junichi KameokaDepartment of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Hideo HarigaeDepartment of Hematology, Tohoku University Hospital, Japan.
Tohoku University Hospital · JPTohoku Medical and Pharmaceutical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia accompanied by an aggressive clinical course and dismal prognosis. We herein report a case of AMKL preceded by mediastinal germ cell tumor that relapsed early after allogeneic hematopoietic stem cell transplantation with myeloablative conditioning but was successfully treated using salvage cord blood transplantation (CBT) with reduced-intensity conditioning. Although several serious complications developed, sustained remission with a favorable general condition was ultimately achieved. Although an optimal therapeutic strategy remains to be established, the graft-versus-leukemia effect of CBT may be promising, even for the treatment of refractory AMKL.

Indexed as

Cord Blood Stem Cell TransplantationHematopoietic Stem Cell TransplantationLeukemia, Megakaryoblastic, AcuteHumansSalvage TherapyTransplantation Conditioningacute megakaryoblastic leukemiaallogeneic hematopoietic stem cell transplantationcord blood transplantationdisseminated fusariosismediastinal germ cell tumor

Identifiers

PMID33814495
PMCPMC8502674
OpenAlexW3147531082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.