ArticleJournal of Alzheimer's disease : JAD2021
Impact of Social Isolation on People with Dementia and Their Family Caregivers.
Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 8 syntheses or guidelines pooled it, 115 citations in OpenAlex.
- Interventions to Reduce Loneliness in Informal Caregivers of People With Dementia: A Systematic Review.Journal of clinical nursing · 2026Pooled it
- The Global Impact of COVID-19 Control Measures on People With Dementia Living at Home and Their Carers: A Systematic Review of Quantitative and Qualitative Research Across 27 Countries.Brain and behavior · 2025Pooled it
- Global trends in dementia care research in the context of COVID-19: bibliometric analysis.Frontiers in medicine · 2024Pooled it
- The impact of social isolation from COVID-19-related public health measures on cognitive function and mental health among older adults: A systematic review and meta-analysis.Ageing research reviews · 2023Pooled it
- The early impacts of COVID-19 on people living with dementia: part I of a mixed-methods systematic review.Aging & mental health · 2023Pooled it
- The early impacts of COVID-19 on unpaid carers of people living with dementia: part II of a mixed-methods systematic review.Aging & mental health · 2023Pooled it
- The Effects of COVID-19 lockdown on neuropsychiatric symptoms in patients with dementia or mild cognitive impairment: A systematic review and meta-analysis.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2022Pooled it
- The Mental Health of Caregivers and Their Patients With Dementia During the COVID-19 Pandemic: A Systematic Review.Frontiers in psychology · 2021Pooled it
- Beyond Caregiving: Recovery and Growth Among Primary Caregivers Following the Loss of a Family Member Living With Dementia.International journal of geriatric psychiatry · 2026Article
- Social Networks and Longitudinal Neuropsychiatric Symptom Trajectories across the Cognitive Continuum.European neurology · 2026Article
- Theory of Mind Deficits and Awareness in Alzheimer's Disease.Dementia and geriatric cognitive disorders · 2026Article
- A Feasibility Study of a Community-Based Program for Individuals Living With Dementia.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2026Article
- Online interventions for dementia caregiver burden and self-efficacy: A systematic review and meta-analysis.International journal of nursing studies advances · 2026Review
- Age at dementia diagnosis, subtype associations, and neuroimaging differentiation in Bangladesh: The CARED study.PloS one · 2026Observational
- Using Photovoice to investigate the lived experiences of family care partners of people living with dementia: What supports their well-being in a care relationship?Frontiers in public health · 2026Article
- Dementia and hearing loss: from risk to mechanisms and management.Frontiers in dementia · 2026Review
- Dementia care shifted towards outpatient services during the COVID-19 pandemic in Germany.Journal of Alzheimer's disease : JAD · 2025Article
- Relationship between stigma, psychological resilience, and social alienation in patients with advanced lung cancer and their caregivers: An actor-partner interdependence mediation model.Asia-Pacific journal of oncology nursing · 2025Article
- Transitions to Long-Term Care for People Living with Dementia: Social Death and Social (Dis) Connections.Nursing reports (Pavia, Italy) · 2025Article
- Perceptions of care and family support from patients and family caregivers during the COVID-19 pandemic: a phenomenological study in Spain.BMC nursing · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 9 institutions in 3 countries.
Funding
Abstract
backgroundPeople with dementia and their family caregivers may face a great burden through social isolation due to the COVID-19 pandemic, which can be manifested as various behavioral and clinical symptoms.
objectiveTo investigate the impacts of social isolation due to the COVID-19 pandemic on individuals with dementia and their family caregivers.
methodsTwo semi-structured questionnaires were applied via telephone to family caregivers of people diagnosed with dementia in three cities in Argentina, Brazil, and Chile, in order to assess clinical and behavioral changes in people with dementia and in their caregivers.
resultsIn general, 321 interviews were conducted. A significant decline in memory function has been reported among 53.0%of people with dementia. In addition, 31.2%of individuals with dementia felt sadder and 37.4%had increased anxiety symptoms. These symptoms of anxiety were greater in individuals with mild to moderate dementia, while symptoms of agitation were greater in individuals with severe dementia. Moreover, compulsive-obsessive behavior, hallucinations, increased forgetfulness, altered appetite, and increased difficulty in activities of daily living were reported more frequently among individuals with moderate to severe dementia. Caregivers reported feeling more tired and overwhelmed during this period and these symptoms were also influenced by the severity of dementia.
conclusionSocial isolation during the COVID-19 pandemic triggered a series of negative behavioral repercussions, both for people with dementia and for their family caregivers in these three South American countries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.