Evidence map›Paper›PMID 33813968›Full record

ArticleVascular medicine (London, England)2021

The impact of standing desks on cardiometabolic and vascular health.

Ariel Bodker, Alexis Visotcky, David Gutterman, Michael E Widlansky, Jacquelyn Kulinski

Erratum issued Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Vascular medicine (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05585190 (Stand Up for Your Health), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05585190 narecruitingnot on this mapstarted 2023, after this paper: background citation

Stand Up for Your Health: A Randomized Study

TypeinterventionalSponsorMedical College of WisconsinRan2023 to 2027Enrolled198ConditionsPre Diabetes, Obesity, Metabolic Syndrome, Sedentary BehaviorArmsControl, Sit-Stand Desk at Work
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Obesity and cardiovascular health.European journal of preventive cardiology · 2024
    Review
  11. Article
  12. Article
  13. Taking the Obesity Paradox to New Heights in Cerebral Atherosclerosis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ariel BodkerDepartment of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Alexis VisotckyInstitute for Health and Equity, Medical College of Wisconsin, Milwaukee, WI, USA.
David GuttermanDepartment of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Michael E WidlanskyDepartment of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0002-1461-9707
Jacquelyn KulinskiDepartment of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0002-1517-7197
Medical College of Wisconsin · US

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
Impact of L. plantarum 299v Supplementation on Endothelial Function and Systemic InflammationR01HL144098 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2019 to 2022
$2.9M
Endothelial function in human diabetes: role of mitochondrial fission proteinsR01HL128240 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2016 to 2020
$2.9M
Institutional Career Development CoreKL2TR001438 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2015 to 2024
$2.9M
Impact of L. plantarum 299v supplementation on endothelial function and inflammation in humans with type 2 diabetesK24HL152143 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2021 to 2025
$572k
NCATS NIH HHS KL2 TR001438NCATS NIH HHS UL1 TR001436NHLBI NIH HHS K24 HL152143NHLBI NIH HHS R01 HL144098
6 · The paper itself

Abstract

Sedentary behavior is associated with cardiovascular disease (CVD) and mortality, independent of physical activity. The biological mechanisms underlying these associations are largely unknown. We hypothesized that obese subjects with sedentary desk jobs, when assigned a sit-stand desk, will reduce daily sedentary time, and show improvement in arterial flow-mediated dilation (FMD), an early indicator of CVD. Overweight and obese subjects without known CVD were recruited at our institution and given an adjustable sit-stand desk at work. Activities were quantified with an accelerometer for 7 days at baseline and during the intervention. FMD of the brachial and superficial femoral arteries, fasting lipids, insulin and glucose labs, and anthropometrics were measured at baseline, and 12 and 24 weeks. Repeated one-way ANOVA tests were used to compare measurements over time. Fifteen participants were enrolled (93% female, mean age 40 ± 5 years, mean body mass index [BMI] 33 ± 5). Mean daily sedentary time at work decreased by 90 minutes from baseline (385 ± 49 minutes) to 12 weeks (297 ± 80 minutes,

Indexed as

Cardiovascular DiseasesWorkplaceAdultExerciseFemaleHumansMaleMiddle AgedObesitySedentary Behaviorflow-mediated vasodilation (FMD)insulin resistanceobesitysedentary lifestyle

Identifiers

PMID33813968
PMCPMC9578685
OpenAlexW3152444702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.