ArticleHypertension (Dallas, Tex. : 1979)2021
Neutrophil Extracellular Traps Promote the Development of Intracranial Aneurysm Rupture.
Open access · bronzeAbstract read
In one paragraph
Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- The association between hematologic traits and aneurysm-related subarachnoid hemorrhage: a two-sample mendelian randomization study.Scientific reports · 2024Pooled it
- Intracranial aneurysms as a manifestation of premature vascular aging: Cellular senescence, inflammaging, and wall degeneration.Ageing research reviews · 2026Review
- Roles of Sirtuin-1 in the Prevention of Intracranial Aneurysm Rupture in Mice.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Achievement and Future Prospectives from Translational Research Targeting Intracranial Aneurysm.Neurologia medico-chirurgica · 2026Review
- A 'Tangled Web' in the CNS: unraveling neutrophil extracellular traps in neurological disorders.Molecular neurodegeneration · 2026Review
- A wide-necked saccular aneurysm of the middle cerebral artery bifurcation with neck atherosclerosis mimicking a fusiform aneurysm: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Peptidylarginine deiminase 4 is a differential regulator of salt-sensitive and salt-resistant hypertension.iScience · 2026Article
- Diagnostic value of inflammatory indexes combined with myocardial enzymes for aneurysmal subarachnoid hemorrhage in patients with intracranial aneurysms.IBRO neuroscience reports · 2025Article
- Evaluation of radiogenomics for risk stratification of intracranial aneurysms: a pilot study.Neuroradiology · 2025Article
- Evaluation of Radiogenomics for Risk Stratification of Intracranial Aneurysms: A Pilot Study.Research square · 2025Article
- A novel neutrophil extracellular traps related diagnostic signature for intracranial aneurysm.BMC neurology · 2025Article
- Animal Models of Intracranial Aneurysms: History, Advances, and Future Perspectives.Translational stroke research · 2025Review
- Discrepancies between human and murine model cerebral aneurysms at single-cell resolution.Frontiers in cell and developmental biology · 2025Article
- Article
- Redundant role of PAD2 and PAD4 in the development of cardiovascular lesions in a mouse model of Kawasaki disease vasculitis.Clinical and experimental immunology · 2024Article
- The neutrophil extracellular traps in neurological diseases: an update.Clinical and experimental immunology · 2024Review
- Clopidogrel Is Associated with Reduced Likelihood of Aneurysmal Subarachnoid Hemorrhage: a Multi-Center Matched Retrospective Analysis.Translational stroke research · 2024Article
- Aspirin treatment for unruptured intracranial aneurysms: Focusing on its anti-inflammatory role.Heliyon · 2024Review
- Decoding the biology and clinical implication of neutrophils in intracranial aneurysm.Annals of clinical and translational neurology · 2024Article
- CNS-associated macrophages contribute to intracerebral aneurysm pathophysiology.Acta neuropathologica communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Masaaki KoraiBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
James PurcellBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Yoshinobu KamioBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Kazuha MitsuiBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Hajime FurukawaBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Kimihiko YokosukaBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Takeshi MiyamotoBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Hitomi SatoBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Hiroki SatoBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Satoru EguchiCardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA (S.E.).
Jinglu AiBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Michael T LawtonBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Tomoki HashimotoBarrow Aneurysm and AVM Research Center (M.K., J.P., Y.K., K.M., H.F., K.Y., T.M., Hitomi Sato, Hiroki Sato, J.A., M.T.L., T.H.), Barrow Neurological Institute, Phoenix, AZ.
Barrow Neurological Institute · USTemple University · US
Funding
EGF-ADAM17 axis in the pathophysiology of intracranial aneurysmR01NS109382 · NINDS · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI EGUCHI, SATORU, HASHIMOTO, TOMOKI · 2019 to 2023
$2.2MMechanisms for intracranial aneurysm ruptureR01NS109584 · NINDS · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI HASHIMOTO, TOMOKI · 2020 to 2024
$1.9MThe Role of Mast Cells in the Pathophysiology of Intracranial AneurysmR01NS082280 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HASHIMOTO, TOMOKI · 2013 to 2017
$1.7MNINDS NIH HHS R01 NS082280NINDS NIH HHS R01 NS109382NINDS NIH HHS R01 NS109584
Abstract
[Figure: see text].
Indexed as
Aneurysm, RupturedAnimalsBrainExtracellular TrapsHumansIntracranial AneurysmMiceextracellular trapinflammationintracranial aneurysmmiceneutrophil
Identifiers
What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.