ArticleAging clinical and experimental research2021
Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital.
Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Risk factors of delirium after cardiac surgery: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2024Pooled it
- Outcomes of postoperative delirium in patients undergoing cardiac surgery: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Potential Markers of Neurocognitive Disorders After Cardiac Surgery: A Bibliometric and Visual Analysis.Frontiers in aging neuroscience · 2022Pooled it
- Pooled it
- Effect of tourniquet technique on postoperative delirium in elderly patients with total knee arthroplasty: a randomized single-blind controlled trial.BMC anesthesiology · 2022Trial
- Feasibility, acceptability, and preliminary estimates of a multimodal AKTIVER Heart Delirium Prevention Program in patients indicated for cardiac surgery: study protocol of a randomized controlled PREVENT POstoperative Delirium (PREVENT-POD) Pilot Study.Pilot and feasibility studies · 2026Article
- Goal-directed multimodal analgesia to enhance recovery after coronary artery bypass grafting: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
- Postoperative Delirium After Coronary Artery Bypass Grafting in the United States, 2016-2021: Trends, Risk Factors, and Outcomes.Journal of cardiothoracic and vascular anesthesia · 2026Observational
- A virtual reality-based multicomponent intervention program for preventing postoperative delirium in the intensive care unit for cardiac surgery patients: from evidence-based design to a pilot trial.Frontiers in medicine · 2026Article
- Fusion of clinical magnet resonance images and electronic health records promotes multimodal predictions of postoperative delirium.Scientific reports · 2025Article
- Preoperative brain volume loss is associated with postoperative delirium in advanced heart failure patients supported by left ventricular assist device.Scientific reports · 2025Article
- Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory.Journal of cardiothoracic surgery · 2024Article
- [Prevalence and risk factors of delirium of older adults after cardiac surgery at the intensive care unit: A retrospective study].Journal of Korean gerontological nursing · 2024Article
- Elderly patients benefit from minimally invasive mitral valve surgery: perioperative risk management matters.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Functional intervention following cardiac surgery to prevent postoperative delirium in older patients (FEEL WELL study).Journal of intensive care · 2023Article
- The Efficacy of Dexmedetomidine alone or with Melatonin on Delirium after Coronary Artery Bypass Graft Surgery: A Randomized Clinical Trial.Anesthesiology and pain medicine · 2023Article
- A Cross-Sectional, Retrospective, and Comparative Study between Delirium and Non-Delirium Psychiatric Disorders in a Psychogeriatric Inpatient Population Referred to Consultation-Liaison Psychiatry Unit.Medicina (Kaunas, Lithuania) · 2023Observational
- Standardized pharmacological management of delirium after on-pump cardiac surgery reduces ICU stay and ventilation in a retrospective pre-post study.Scientific reports · 2023Observational
- Elective Ascending Aortic Aneurysm Surgery in the Elderly.Journal of clinical medicine · 2023Article
- Isolated annuloplasty in elderly patients with secondary mitral valve regurgitation: short- and long-term outcomes with a less invasive approach.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPostoperative delirium (POD) is a relevant and underdiagnosed complication after cardiac surgery that is associated with increased intensive care unit (ICU) and hospital length of stay (LOS). The aim of this subgroup study was to compare the frequency of tested POD versus the coded International Statistical Classification of Diseases and Related Health Problems (ICD) diagnosis of POD and to evaluate the influence of POD on LOS in ICU and hospital.
methods254 elective cardiac surgery patients (mean age, 70.5 ± 6.4 years) at the University Hospital Bonn between September 2018 and October 2019 were evaluated. The endpoint tested POD was considered positive, if one of the tests Confusion Assessment Method for ICU (CAM-ICU) or Confusion Assessment Method (CAM), 4 'A's Test (4AT) or Delirium Observation Scale (DOS) was positive on one day.
resultsPOD occurred in 127 patients (50.0%). LOS in ICU and hospital were significantly different based on presence (ICU 165.0 ± 362.7 h; Hospital 26.5 ± 26.1 days) or absence (ICU 64.5 ± 79.4 h; Hospital 14.6 ± 6.7 days) of POD (p < 0.001). The multiple linear regression showed POD as an independent predictor for a prolonged LOS in ICU (48%; 95%CI 31-67%) and in hospital (64%; 95%CI 27-110%) (p < 0.001). The frequency of POD in the study participants that was coded with the ICD F05.0 and F05.8 by hospital staff was considerably lower than tests revealed by the study personnel.
conclusionApproximately 50% of elderly patients who underwent cardiac surgery developed POD, which is associated with an increased ICU and hospital LOS. Furthermore, POD is highly underdiagnosed in clinical routine.
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