ArticleEuropean child & adolescent psychiatry2022
Characterizing the heterogeneous course of inattention and hyperactivity-impulsivity from childhood to young adulthood.
Article in European child & adolescent psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Infant Habituation Task Performance Is Associated With Familial Risk for Attention-Deficit/Hyperactivity Disorder.JAACAP open · 2026Article
- Dissecting the shared genetic architecture between testosterone traits and attention-deficit/hyperactivity disorder.European child & adolescent psychiatry · 2026Article
- ADHD symptom trajectories and brain morphometry: A longitudinal analysis.medRxiv : the preprint server for health sciences · 2026Article
- The Influence of Noise Perception and Parent-Rated Developmental Characteristics on White Noise Benefits in Children.Journal of eye movement research · 2026Article
- From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Developmental Pathways of Inattention, Hyperactivity/Impulsivity, and Disruptive Behaviors: A Longitudinal, Person-Centered Approach.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Attention-deficit/hyperactivity disorder (ADHD) in adults: evidence base, uncertainties and controversies.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Development of inattention and executive dysfunction in youth with spina bifida: condition severity variables as predictors.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025Article
- Early Childhood Emotion Regulation Strategy Articulation, its Neurophysiological Correlates, and Association with Psychopathology.Translational issues in psychological science · 2024Article
- No Effects of Auditory and Visual White Noise on Oculomotor Control in Children with ADHD.Journal of attention disorders · 2024Article
- The Emotional Impact of Family Involvement during Homework in Children with Neurodevelopmental Disorders: A Systematic Review.Children (Basel, Switzerland) · 2024Review
- The Impact of Children's and Parents' Perceptions of Parenting Styles on Attention, Hyperactivity, Anxiety, and Emotional Regulation.Children (Basel, Switzerland) · 2024Article
- Attention-deficit/hyperactivity disorder.Nature reviews. Disease primers · 2024Review
- The ADHD Assessment Quality Assurance Standard for Children and Teenagers (CAAQAS).Neuropsychiatric disease and treatment · 2024Article
- Low Persistence of Inattention Symptoms From Childhood to Adolescence: A Population-Based Study.Journal of attention disorders · 2023Article
- Sex differences in the course of autistic and co-occurring psychopathological symptoms in adolescents with and without autism spectrum disorder.Autism : the international journal of research and practice · 2023Article
- Benefits of a 12-Week Non-Drug "Brain Fitness Program" for Patients with Attention-Deficit/Hyperactive Disorder, Post-Concussion Syndrome, or Memory Loss.Journal of Alzheimer's disease reports · 2023Article
- Triple Diagnosis of Attention-Deficit/Hyperactivity Disorder with Coexisting Bipolar and Alcohol Use Disorders: Clinical Aspects and Pharmacological Treatments.Current neuropharmacology · 2023Review
- Heterotypic and homotypic continuity in psychopathology: a narrative review.Frontiers in psychology · 2023Review
- Heterogeneous courses of obsessive-compulsive disorders-better data on a lifetime perspective urgently needed.European child & adolescent psychiatry · 2022Article
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10 authors at 5 institutions in 3 countries.
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Abstract
To advance understanding of the heterogeneity in the course of ADHD, joint symptom trajectories of inattention and hyperactivity-impulsivity from childhood to young adulthood were modelled and associated with genetic, demographic, and clinical characteristics. Data were obtained from the NeuroIMAGE cohort which includes 485 individuals with ADHD, their 665 siblings, and 399 typically developing children. Trajectories were based on scores of the Conners Parent Rating Scale Revised and estimated over seven homogeneous age bins (from 5 to 28 years) using parallel process latent class growth analysis on data collected across 2-4 time points. Multilevel multinomial logistic regression was used to identify characteristics that differentiated between the derived classes. A seven-class solution revealed "severe combined stable" (4.8%), "severe combined decreasing" (13%), "severe inattentive stable" (4.8%), "moderate combined increasing" (7.5%), "moderate combined decreasing" (12.7%), "stable mild" (12.9%), and "stable low" (44.3%) classes. Polygenic risk for depression, ADHD diagnosis, ADHD medication use, IQ, comorbid symptom levels (foremost oppositional behaviour), and functional impairment levels differentiated classes with similar ADHD symptom levels in childhood but a diverging course thereafter. The course of ADHD is highly heterogeneous, with stable, decreasing, and increasing trajectories. Overall, severe symptom levels in childhood are associated with elevated-to-severe symptom levels in adolescence and young adulthood, despite substantial symptom reductions. Beyond symptom severity in childhood, genetic, demographic, and clinical characteristics distinguish the heterogeneous course.
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