Evidence map›Paper›PMID 33813159›Full record

ReviewCurrent opinion in microbiology2021

Introducing noncanonical amino acids for studying and engineering bacterial microcompartments.

Hao Chen, Jessica Wilson, Sara Ottinger, Qinglei Gan, Chenguang Fan

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao ChenCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA.
Jessica WilsonCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA.
Sara OttingerDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR, USA.
Qinglei GanDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR, USA.
Chenguang FanCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA; Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR, USA. Electronic address: cf021@uark.edu.

Funding

The role of lysine acetylation of human threonyl-tRNA synthetaseR15GM140433 · NIGMS · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI FAN, CHENGUANG · 2021 to 2021
$450k
NIGMS NIH HHS R15 GM140433
6 · The paper itself

Abstract

Bacterial microcompartments (BMCs) with selectively permeable shells and encapsulated enzyme cores are well-suited candidates for nano-bioreactors because of their advantages of enhancing pathway flux and protection against toxic products. To better study and engineer protein-based BMCs, a series of protein chemistry approaches are adopted. As one of the most advanced techniques, genetic code expansion can introduce various noncanonical amino acids (ncAAs) with diverse functional groups into target proteins, thus providing powerful tools for protein studies and engineering. This review summarizes and proposes useful tools based on current development of the genetic code expansion technique towards challenges in BMC studies and engineering.

Indexed as

Amino AcidsBacteriaBacterial ProteinsAmino AcidsBacterial Proteins

Identifiers

PMID33813159
PMCPMC8169543

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.