Evidence map›Paper›PMID 33812935›Full record

ReviewNeuroscience letters2021

Mini-review: Microtubule sliding in neurons.

Shrobona Guha, Ankita Patil, Hemalatha Muralidharan, Peter W Baas

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Motor-Assisted Co-Migration of Intracellular Organelles and Microtubules as a Mechanism for Directed Cargo Transport.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  4. Article
  5. Regulation of Axonal Microtubule Polarity Orientation in Different Kinds of Neurons.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  6. Review
  7. Article
  8. Nuclear movement in multinucleated cells.Development (Cambridge, England) · 2022
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shrobona GuhaDrexel University College of Medicine, Department of Neurobiology and Anatomy, 2900 Queen Lane, Philadelphia, PA, 19129, United States.
Ankita PatilDrexel University College of Medicine, Department of Neurobiology and Anatomy, 2900 Queen Lane, Philadelphia, PA, 19129, United States.
Hemalatha MuralidharanDrexel University College of Medicine, Department of Neurobiology and Anatomy, 2900 Queen Lane, Philadelphia, PA, 19129, United States.
Peter W BaasDrexel University College of Medicine, Department of Neurobiology and Anatomy, 2900 Queen Lane, Philadelphia, PA, 19129, United States. Electronic address: pwb22@drexel.edu.
Drexel University · US

Funding

MICROTUBULE DYNAMICS AND AXON GROWTHR01NS028785 · NINDS · UNIVERSITY OF WISCONSIN MADISON · PI BAAS, PETER W. · 1990 to 2021
$7.3M
Mechanisms of SPG4 Hereditary Spastic ParaplegiaR01NS118177 · NINDS · DREXEL UNIVERSITY · PI BAAS, PETER W., MORFINI, GERARDO ANDRES · 2020 to 2024
$3.2M
Role of Tau in Microtubule Stability in Adult NeuronsR21AG068597 · NIA · DREXEL UNIVERSITY · PI BAAS, PETER W. · 2021 to 2021
$416k
Using multiple species, stimuli, and tasks to study the neural basis of visually guided behaviorK99NS118117 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NI, AMY MEESUN · 2020 to 2021
$239k
NIA NIH HHS R21 AG068597NINDS NIH HHS K99 NS118117NINDS NIH HHS R01 NS028785NINDS NIH HHS R01 NS118177
6 · The paper itself

Abstract

Microtubule sliding is an underappreciated mechanism that contributes to the establishment, organization, preservation, and plasticity of neuronal microtubule arrays. Powered by molecular motor proteins and regulated in part by static crosslinker proteins, microtubule sliding is the movement of microtubules relative to other microtubules or to non-microtubule structures such as the actin cytoskeleton. In addition to other important functions, microtubule sliding significantly contributes to the establishment and maintenance of microtubule polarity patterns in different regions of the neuron. The purpose of this article is to review the state of knowledge on microtubule sliding in the neuron, with emphasis on its mechanistic underpinnings as well as its functional significance.

Indexed as

AnimalsAxonsCell DifferentiationCell MovementCell PolarityDendritesDyneinsHumansMicrotubulesNeuronsDyneinsAxonCytoplasmic dyneinKIFC1Kinesin-1MicrotubuleMicrotubule crosslinkingMicrotubule polarity orientationMicrotubule polarity sortingMicrotubule slidingMicrotubule transportTRIM46

Identifiers

PMID33812935
PMCPMC8097519
OpenAlexW3145808008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.