Evidence map›Paper›PMID 33812458›Full record

ArticleParasite (Paris, France)2021

Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against ear mite (Otodectes cynotis) infestations in cats.

Eric Tielemans, Joe Prullage, Otsuki Tomoko, Julian Liebenberg, Balázs Capári, Smaragda Sotiraki, Despoina Kostopoulou, Panagiota Ligda, Michael Ulrich, Martin Knaus

Open access · goldAbstract read
In one paragraph

Article in Parasite (Paris, France), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. The most effective systemic treatment in cats with otodectic mange: A critically appraised topic.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 6 countries.

Eric TielemansBoehringer-Ingelheim Animal Health, 29 Avenue Tony Garnier, 69007 Lyon, France.ORCID 0000-0003-4798-3246
Joe PrullageBoehringer-Ingelheim Animal Health, Missouri Research Center, 6498 Jade Rd., Fulton, 65251 MO, USA.
Otsuki TomokoBoehringer Ingelheim Animal Health Japan Co Ltd, ThinkPark Tower, 2-1-1 Osaki, Shinagawa-ku, 141-6017 Tokyo, Japan.
Julian LiebenbergClinvet International (Pty) Ltd., P.O. Box 11186, Universitas, 9321 Bloemfontein, Republic of South Africa.
Balázs CapáriKapriol Bt., Vak Bottyán St. 1, 8330 Sümeg, Hungary.
Smaragda SotirakiVeterinary Research Institute, ELGO-DIMITRA Campus, Thermi, 57001 Thessaloniki, Greece.
Despoina KostopoulouVeterinary Research Institute, ELGO-DIMITRA Campus, Thermi, 57001 Thessaloniki, Greece.
Panagiota LigdaVeterinary Research Institute, ELGO-DIMITRA Campus, Thermi, 57001 Thessaloniki, Greece.
Michael UlrichCheri-Hill Kennel & Supply Inc., 17190 Polk Rd., Stanwood, 49346 MI, USA.
Martin KnausBoehringer-Ingelheim Vetmedica GmbH, Kathrinenhof Research Center, Walchenseestr. 8-12, 83101 Rohrdorf, Germany.
Centre for Research and Technology Hellas · GRBoehringer Ingelheim (Japan) · JPBoehringer Ingelheim (United States) · USClinvet · ZADépartement Santé Animale · FRRoche (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel, nematodicidal and cestodicidal compounds, in NexGard

Indexed as

Cat DiseasesMite InfestationsMitesAnimalsCatsEuropeIvermectinPraziquantelSouth AfricaTreatment OutcomeeprinomectinIvermectinPraziquantelCatEar miteEfficacyEsafoxolanerOtodectes cynotis

Identifiers

PMID33812458
PMCPMC8019571
OpenAlexW3140332583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.