ArticleAmerican journal of physical anthropology2021
Novel strategies for the characterization of cancellous bone morphology: Virtual isolation and analysis.
Article in American journal of physical anthropology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 15 citations in OpenAlex.
- Whole-Epiphysis Trabecular Bone in Tamarin Limbs Suggests Effects of Leaping Distance Alongside Non-Biomechanical Factors.American journal of biological anthropology · 2026Article
- Identification of functionally related adaptations in the trabecular network of the proximal femur and tibia of a bipedally trained Japanese macaque.Anthropological science : journal of the Anthropological Society of Nippon = Jinruigaku zasshi · 2024Article
- Preparing computed tomography images for machine learning in forensic and virtual anthropology.Forensic science international. Synergy · 2023Article
- Novel strategies for the characterization of cancellous bone morphology: Virtual isolation and analysis.American journal of physical anthropology · 2021Article
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Authors and funding
5 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe advent of micro-computed tomography (μCT) made cancellous bone more accessible than ever before. Nevertheless, the characterization of cancellous bone is made difficult by its inherent complexity and the difficulties in defining homology across datasets. Here we propose novel virtual methodological approaches to overcome those issues and complement existing methods. MATERIALS AND
methodsWe present a protocol for the isolation of the whole cancellous region within a μCT scanned bone. This method overcomes the subsampling issues and allows studying cancellous bone as a single unit. We test the protocol on a set of primate bones. In addition, we describe a set of morphological indices calculated on the topological skeleton of the cancellous bone: node density, node connectivity, trabecular angle, trabecular tortuosity, and fractal dimension. The usage of the indices is shown on a small comparative sample of primate femoral heads.
resultsThe isolation protocol proves reliable in isolating cancellous structures from several different bones, regardless of their shape. The indices seem to detect some functional differences, although further testing on comparative samples is needed to clarify their potential for the study of cancellous architecture.
conclusionsThe approaches presented overcome some of the difficulties of trabecular bone studies. The methods presented here represent an alternative or supporting method to the existing tools available to address the biomechanics of cancellous bone.
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