Evidence map›Paper›PMID 33811580›Full record

ReviewMolecular and cellular biochemistry2021

Apolipoprotein-AI and AIBP synergetic anti-inflammation as vascular diseases therapy: the new perspective.

Ampadu O Jackson, Ganiyu A Rahman, Shiyin Long

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Expression of recombinant human Apolipoprotein A-IBioresources and bioprocessing · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ampadu O JacksonDepartment of Biochemistry and Molecular Biology, University of South China, Hengyang, 421001, Hunan Province, China.ORCID http://orcid.org/0000-0002-7322-9039
Ganiyu A RahmanDepartment of Surgery, School of Medicine, Cape Coast Teaching Hospital, University of Cape Coast, Cape Coast, Ghana.
Shiyin LongDepartment of Biochemistry and Molecular Biology, University of South China, Hengyang, 421001, Hunan Province, China. longshiyin@126.com.
University of Cape Coast · GHUniversity of South China · CN

Funding

Natural Science Foundation of Hunan Province 2018JJ2346
6 · The paper itself

Abstract

Vascular diseases (VDs) including pulmonary arterial hypertension (PAH), atherosclerosis (AS) and coronary arterial diseases (CADs) contribute to the higher morbidity and mortality worldwide. Apolipoprotein A-I (Apo A-I) binding protein (AIBP) and Apo-AI negatively correlate with VDs. However, the mechanism by which AIBP and apo-AI regulate VDs still remains unexplained. Here, we provide an overview of the role of AIBP and apo-AI regulation of vascular diseases molecular mechanisms such as vascular energy homeostasis imbalance, oxidative and endoplasmic reticulum stress and inflammation in VDs. In addition, the role of AIBP and apo-AI in endothelial cells (ECs), vascular smooth muscle (VSMCs) and immune cells activation in the pathogenesis of VDs are explained. The in-depth understanding of AIBP and apo-AI function in the vascular system may lead to the discovery of VDs therapy.

Indexed as

Apolipoprotein A-IDNA-Binding ProteinsHumansInflammationSignal TransductionVascular DiseasesAPOA1 protein, humanApolipoprotein A-IAUNIP protein, humanDNA-Binding ProteinsAIBP: apolipoprotein-AI: ATP: oxidation stressCoronary arterial diseasesImmune cells: atherosclerosisInflammation: endothelial cellPulmonary arterial hypertensionVascular smooth muscle cell

Identifiers

PMID33811580
OpenAlexW3151647476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.