Evidence map›Paper›PMID 33811576›Full record

ArticleMolecular biology reports2021

Stevia rebaudiana germplasm characterization using microsatellite markers and steviol glycosides quantification by HPLC.

Maria Margarida Ribeiro, Tatiana Diamantino, Joana Domingues, Ílio Montanari, Marcos Nopper Alves, José Carlos Gonçalves

Open access · hybridAbstract read
In one paragraph

Article in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Patterns of Genetic and Clonal Diversity inPlants (Basel, Switzerland) · 2025
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  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Maria Margarida RibeiroCentro de Biotecnologia de Plantas da Beira Interior, Escola Superior Agrária de Castelo Branco, 6001-909, Castelo Branco, Portugal. mataide@ipcb.pt.ORCID http://orcid.org/0000-0003-4684-1262
Tatiana DiamantinoCentro de Biotecnologia de Plantas da Beira Interior, Escola Superior Agrária de Castelo Branco, 6001-909, Castelo Branco, Portugal.ORCID http://orcid.org/0000-0002-1659-4398
Joana DominguesCentro de Biotecnologia de Plantas da Beira Interior, Escola Superior Agrária de Castelo Branco, 6001-909, Castelo Branco, Portugal.ORCID http://orcid.org/0000-0002-2992-4173
Ílio MontanariCPQBA/UNICAMP - Centro Pluridisciplinar de Pesquisas Químicas Biológicas e Agrícolas, Universidade Estadual de Campinas, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-3214-5250
Marcos Nopper AlvesCPQBA/UNICAMP - Centro Pluridisciplinar de Pesquisas Químicas Biológicas e Agrícolas, Universidade Estadual de Campinas, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-2000-6499
José Carlos GonçalvesCentro de Biotecnologia de Plantas da Beira Interior, Escola Superior Agrária de Castelo Branco, 6001-909, Castelo Branco, Portugal.ORCID http://orcid.org/0000-0003-3387-4487
Polytechnic Institute of Castelo Branco · PTUniversidade Estadual de Campinas (UNICAMP) · BRUniversity of Lisbon · PT

Funding

Fundação para a Ciência e a Tecnologia UIDB/00239/2020Fundação para a Ciência e a Tecnologia UIDB/00681/2020
6 · The paper itself

Abstract

Stevia rebaudiana Bertoni, Asteraceae, is an herbaceous perennial plant native to Paraguay. This species is considered since ancient times a medicinal plant with important bioactive compounds and pharmacologic and food properties, namely diterpenes glycosides. The high natural sweetener potential stevioside and rebaudioside A produced by S. rebaudiana plants are suitable sucrose substitutes, and their obtention is influenced by environmental, phytosociological, and genetic factors. The plants' genetic profile and sweet potential depiction are needed for suitable plant selection for improvement and deployment. Thirty-one S. rebaudiana accessions grown in the same plot where leaves samples were collected in early 2019, were genotyped using six microsatellite markers, including two steviol glycosides biosynthesis functionally involved markers. Additionally, an aqueous extract of each sample was obtained in a water bath and purified by SPE for stevioside and rebaudioside A quantification by normal phase HPLC. Stevioside and rebaudioside A contents varied between 0.53-7.36% (w w

Indexed as

Chromatography, High Pressure LiquidCluster AnalysisDiterpenes, KauraneGenetic LociGenetic VariationGenotypeGlucosidesGlycosidesMicrosatellite RepeatsPhylogenyPrincipal Component AnalysisSeedsSteviaDiterpenes, KauraneGlucosidesGlycosidesrebaudioside AsteviolsteviosideFingerprintGenetic improvementGermplasmMolecular markersRebaudioside AStevioside

Identifiers

PMID33811576
PMCPMC8060219
OpenAlexW3141408700

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.