Evidence map›Paper›PMID 33811558›Full record

ArticleEuropean journal of applied physiology2021

Post-exercise cardiac autonomic and cardiovascular responses to heart rate-matched and work rate-matched hypoxic exercise.

Alessandro Fornasiero, Andrea Zignoli, Mark Rakobowchuk, Federico Stella, Aldo Savoldelli, Spyros Skafidas, Federico Schena, Barbara Pellegrini, Laurent Mourot

Open access · hybridAbstract read
In one paragraph

Article in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Alessandro FornasieroCeRiSM, Sport Mountain and Health Research Centre, University of Verona, Via Matteo del Ben, 5/b, 38068, Rovereto, Italy. alessandro.fornasiero@gmail.com.ORCID http://orcid.org/0000-0002-8787-6659
Andrea ZignoliCeRiSM, Sport Mountain and Health Research Centre, University of Verona, Via Matteo del Ben, 5/b, 38068, Rovereto, Italy.
Mark RakobowchukDepartment of Biological Sciences, Thompson Rivers University Faculty of Science, Kamloops, Canada.
Federico StellaCeRiSM, Sport Mountain and Health Research Centre, University of Verona, Via Matteo del Ben, 5/b, 38068, Rovereto, Italy.
Aldo SavoldelliCeRiSM, Sport Mountain and Health Research Centre, University of Verona, Via Matteo del Ben, 5/b, 38068, Rovereto, Italy.
Spyros SkafidasCeRiSM, Sport Mountain and Health Research Centre, University of Verona, Via Matteo del Ben, 5/b, 38068, Rovereto, Italy.
Federico SchenaCeRiSM, Sport Mountain and Health Research Centre, University of Verona, Via Matteo del Ben, 5/b, 38068, Rovereto, Italy.
Barbara PellegriniCeRiSM, Sport Mountain and Health Research Centre, University of Verona, Via Matteo del Ben, 5/b, 38068, Rovereto, Italy.
Laurent MourotEA3920 Prognostic Factors and Regulatory Factors of Cardiac and Vascular Pathologies, Exercise Performance Health Innovation (EPHI) platform, University of Bourgogne Franche-Comté, Besançon, France.
University of Verona · ITNational Research Tomsk State University · RUThompson Rivers University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigated the effect of performing hypoxic exercise at the same heart rate (HR) or work rate (WR) as normoxic exercise on post-exercise autonomic and cardiovascular responses.

methodsThirteen men performed three interval-type exercise sessions (5 × 5-min; 1-min recovery): normoxic exercise at 80% of the WR at the first ventilatory threshold (N), hypoxic exercise (FiO

resultsCompared to N, H-WR elicited a higher HR response (≈ 83% vs ≈ 75%HRmax, p < 0.001) and H-HR a reduced exercise WR (- 21.1 ± 9.3%, p < 0.001). Cardiac parasympathetic indices were reduced 15 min after exercise and recovered within 60 min in N and H-HR, but not after H-WR (p < 0.05). H-WR altered cardiac baroreflex sensitivity (cBRS) both at rest and during SS (specifically in the control of blood pressure fall during standing phases) in the first 60 min after the exercise bout (p < 0.05). Post-exercise hypotension (PEH) did not occur in H-HR (p > 0.05) but lasted longer in H-WR than in N (p < 0.05).

conclusionsModerate HR-matched hypoxic exercise mimicked post-exercise autonomic responses of normoxic exercise without resulting in significant PEH. This may relate to the reduced WR and the limited associated mechanical/metabolic strain. Conversely, WR-matched hypoxic exercise impacted upon post-exercise autonomic and cardiovascular responses, delaying cardiac autonomic recovery, temporarily decreasing cBRS and evoking prolonged PEH.

Indexed as

Cardiovascular Physiological PhenomenaAdultAutonomic Nervous SystemBiomarkersExerciseHeart RateHemodynamic MonitoringHumansHypoxiaLactatesMaleBiomarkersLactatesAutonomic nervous systemCardiac baroreflex sensitivityHeart rate variabilityHypoxiaHypoxic exercisePost-exercise hypotension

Identifiers

PMID33811558
PMCPMC8192382
OpenAlexW3147776520

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.