Evidence map›Paper›PMID 33811471›Full record

ArticleCancer reports (Hoboken, N.J.)2021

Surface expression of the immunotherapeutic target G

Malena Wiebel, Sareetha Kailayangiri, Bianca Altvater, Jutta Meltzer, Kay Grobe, Sabine Kupich, Claudia Rossig

Open access · goldAbstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. GD2-Targeting CAR T-cell Therapy for Patients with GD2+ Medulloblastoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  8. Article
  9. Review
  10. Strategies to Overcome Resistance to Immune-Based Therapies in Osteosarcoma.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Article
  13. Surface expression of the immunotherapeutic target GCancer reports (Hoboken, N.J.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Malena WiebelDepartment of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.
Sareetha KailayangiriDepartment of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.
Bianca AltvaterDepartment of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.
Jutta MeltzerDepartment of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.
Kay GrobeInstitute of Physiological Chemistry and Pathobiochemistry, University of Muenster, Muenster, Germany.
Sabine KupichInstitute of Physiological Chemistry and Pathobiochemistry, University of Muenster, Muenster, Germany.
Claudia RossigDepartment of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.ORCID 0000-0002-8672-5285
University Hospital Münster · DEAugenstern · DE

Funding

Deutsche Krebshilfe
6 · The paper itself

Abstract

backgroundChimeric antigen receptor (CAR) T-cell therapy of pediatric sarcomas is challenged by the paucity of targetable cell surface antigens. A candidate target in osteosarcoma (OS) is the ganglioside G

aimWe aimed to identify mechanisms that upregulate G METHODS AND

resultsG

conclusionExpression of G

Indexed as

BenzamidesBiphenyl CompoundsBone NeoplasmsBrefeldin ACell Culture TechniquesCytotoxicity, ImmunologicEnhancer of Zeste Homolog 2 ProteinGangliosidesHumansMorpholinesOsteosarcomaProtein Synthesis InhibitorsPyridonesSurface PropertiesT-LymphocytesTumor Cells, CulturedBenzamidesBiphenyl CompoundsBrefeldin AEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanganglioside, GD2GangliosidesMorpholinesProtein Synthesis InhibitorsPyridonestazemetostatcellular immunotherapychimeric antigen receptorsgangliosidesGD2osteosarcoma

Identifiers

PMID33811471
PMCPMC8551999
OpenAlexW3147134703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.