Evidence map›Paper›PMID 33811451›Full record

ArticleBrain and behavior2021

A mediating role for mental health in associations between COVID-19-related self-stigma, PTSD, quality of life, and insomnia among patients recovered from COVID-19.

Hosein Mahmoudi, Mohsen Saffari, Mahmoud Movahedi, Hormoz Sanaeinasab, Hojat Rashidi-Jahan, Morteza Pourgholami, Ali Poorebrahim, Jalal Barshan, Milad Ghiami, Saman Khoshmanesh and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Brain and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05639855 (Study on Mental Health-related Stigma), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05639855 naunknown statusnot on this map

Study on Mental Health-related Stigma: Attitudes and Values of University Students Towards People With Mental Disorders

TypeinterventionalSponsorNereida Canosa RodríguezRan2021 to 2023Enrolled740ConditionsMental Health DisorderArmsMental Health Literacy Programme
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Stigma, Post-traumatic Stress, and COVID-19 Vaccination Intent in Mongolia, India, and the United States.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hosein MahmoudiTrauma Research Center and Faculty of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Mohsen SaffariHealth Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-7590-9516
Mahmoud MovahediBehavioral Sciences Research Center and Faculty of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Hormoz SanaeinasabHealth Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Hojat Rashidi-JahanHealth Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Morteza PourgholamiHealth Education and Health Promotion unit, Rasht Health Center,Guilan University of Medical Sciences, Rasht, Iran.
Ali PoorebrahimSocial Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
Jalal BarshanRasht Health Center,Guilan University of Medical Sciences, Rasht, Iran.
Milad GhiamiHealth, Safety and Environment Management, Expert of Occupational Health of Health Center, Rasht, Iran.
Saman KhoshmaneshDepartment of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Marc N PotenzaDepartments of Psychiatry and Neuroscience and the Child Study Center, School of Medicine, Yale University, New Haven, CT, USA.
Chung-Ying LinInstitute of Allied Health Sciences, Department of Occupational Therapy, Department of Public Health, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Amir H PakpourSocial Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID 0000-0002-8798-5345

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

introductionPatients with COVID-19 often suffer from psychological problems such as post-traumatic stress disorder (PTSD) and self-stigmatization that may negatively impact their quality of life and sleep. This study examined mental health as a potential mediating factor linking self-stigmatization and PTSD to quality of life and sleep.

methodsUsing a cross-sectional design, 844 people who had recovered from COVID-19 were called and interviewed. Data were collected using structured scales. Structural equation modeling was applied to assess fitness of a mediation model including self-stigma and PTSD as independent factors and quality of life and insomnia as dependent variables.

resultsMental health, COVID-19-related self-stigma, and mental quality of life were associated. Insomnia, PTSD, and COVID-19-related self-stigma displayed significant direct associations (r = .334 to 0.454; p < .01). A mediation model indicated satisfactory goodness of fit (CFI = 0.968, TLI = 0.950, SRMR = 0.071, RMSEA = 0.068). Mental health as a mediator had negative relationships with COVID-19-related self-stigma, PTSD, and insomnia and positive associations with quality of life.

conclusionMental health may mediate effects of COVID-19-related self-stigma and PTSD on quality of life and insomnia. Designing programs to improve mental health among patients with COVID-19 may include efforts to reduce negative effects of PTSD and COVID-19-related self-stigma on quality of life and insomnia.

Indexed as

Quality of LifeSocial StigmaCOVID-19Cross-Sectional StudiesFemaleHumansMaleMental HealthMiddle AgedPost-Acute COVID-19 SyndromeSARS-CoV-2Sleep Initiation and Maintenance DisordersStress Disorders, Post-TraumaticcoronavirusCOVID-19quality of lifesleep disordersstigmatizationstress

Identifiers

PMID33811451
PMCPMC8119851

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.