Evidence map›Paper›PMID 33811362›Full record

ArticleThe International journal of eating disorders2021

Prediction of eating disorder treatment response trajectories via machine learning does not improve performance versus a simpler regression approach.

Hallie Espel-Huynh, Fengqing Zhang, J Graham Thomas, James F Boswell, Heather Thompson-Brenner, Adrienne S Juarascio, Michael R Lowe

Open access · greenAbstract read
In one paragraph

Article in The International journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Individual-Specific Animated Profiles of Mental Health.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hallie Espel-HuynhDrexel University, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-8456-3465
Fengqing ZhangDrexel University, Philadelphia, Pennsylvania, USA.
J Graham ThomasWeight Control and Diabetes Research Center, The Miriam Hospital, Providence, Rhode Island, USA.
James F BoswellUniversity at Albany-SUNY, Albany, New York, USA.
Heather Thompson-BrennerBoston University, Boston, Massachusetts, USA.
Adrienne S JuarascioDrexel University, Philadelphia, Pennsylvania, USA.
Michael R LoweDrexel University, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-6301-9214
Drexel University · USBrown University · USBoston University · USUniversity at Albany, State University of New York · US

Funding

Training in Behavioral & Preventive MedicineT32HL076134 · NHLBI · MIRIAM HOSPITAL · PI John Graham Thomas · 2006 to 2026
$5.7M
NHLBI NIH HHS T32 HL076134
6 · The paper itself

Abstract

objectivePatterns of response to eating disorder (ED) treatment are heterogeneous. Advance knowledge of a patient's expected course may inform precision medicine for ED treatment. This study explored the feasibility of applying machine learning to generate personalized predictions of symptom trajectories among patients receiving treatment for EDs, and compared model performance to a simpler logistic regression prediction model.

methodParticipants were adolescent girls and adult women (N = 333) presenting for residential ED treatment. Self-report progress assessments were completed at admission, discharge, and weekly throughout treatment. Latent growth mixture modeling previously identified three latent treatment response trajectories (Rapid Response, Gradual Response, and Low-Symptom Static Response) and assigned a trajectory type to each patient. Machine learning models (support vector, k-nearest neighbors) and logistic regression were applied to these data to predict a patient's response trajectory using data from the first 2 weeks of treatment.

resultsThe best-performing machine learning model (evaluated via area under the receiver operating characteristics curve [AUC]) was the radial-kernel support vector machine (AUC DISCUSSION: Prediction of ED treatment response trajectories is feasible and achieves excellent performance, however, machine learning added little benefit. We discuss the need to explore how advance knowledge of expected trajectories may be used to plan treatment and deliver individualized interventions to maximize treatment effects.

Indexed as

Feeding and Eating DisordersMachine LearningAdolescentAdultFemaleHospitalizationHumansLogistic ModelsROC Curvefeasibility studiesfeeding and eating disordershealth services researchmachine learningprecision medicinestatistical methodologysupport vector machinetreatment outcome

Identifiers

PMID33811362
PMCPMC8273095
OpenAlexW3139753837

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.