Evidence map›Paper›PMID 33811295›Full record

ReviewSports medicine (Auckland, N.Z.)2021

An Abductive Inference Approach to Assess the Performance-Enhancing Effects of Drugs Included on the World Anti-Doping Agency Prohibited List.

Andreas Breenfeldt Andersen, Glenn A Jacobson, Jacob Bejder, Dino Premilovac, Stephen M Richards, Jon J Rasmussen, Søren Jessen, Morten Hostrup

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sports medicine (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Consensus Statements-Optimizing Performance of the Elite Athlete.Scandinavian journal of medicine & science in sports · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andreas Breenfeldt AndersenDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-3361-3009
Glenn A JacobsonSchool of Pharmacy and Pharmacology, College of Health and Medicine, University of Tasmania, Hobart, Australia.ORCID http://orcid.org/0000-0002-3409-8769
Jacob BejderDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-9698-9188
Dino PremilovacTasmanian School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Australia.ORCID http://orcid.org/0000-0003-2770-4713
Stephen M RichardsTasmanian School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Australia.
Jon J RasmussenDepartment of Endocrinology, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-2898-1771
Søren JessenDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-7461-1264
Morten HostrupDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Copenhagen, Denmark. mhostrup@nexs.ku.dk.ORCID http://orcid.org/0000-0002-6201-2483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some have questioned the evidence for performance-enhancing effects of several substances included on the World Anti-Doping Agency's Prohibited List due to the divergent or inconclusive findings in randomized controlled trials (RCTs). However, inductive statistical inference based on RCTs-only may result in biased conclusions because of the scarcity of studies, inter-study heterogeneity, too few outcome events, or insufficient power. An abductive inference approach, where the body of evidence is evaluated beyond considerations of statistical significance, may serve as a tool to assess the plausibility of performance-enhancing effects of substances by also considering observations and facts not solely obtained from RCTs. Herein, we explored the applicability of an abductive inference approach as a tool to assess the performance-enhancing effects of substances included on the Prohibited List. We applied an abductive inference approach to make inferences on debated issues pertaining to the ergogenic effects of recombinant human erythropoietin (rHuEPO), beta

Indexed as

Doping in SportsPerformance-Enhancing SubstancesPharmaceutical PreparationsHumansTestosterone CongenersPerformance-Enhancing SubstancesPharmaceutical PreparationsTestosterone Congeners

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.