Evidence map›Paper›PMID 33811291›Full record

ArticleWorld journal of urology2023

3D-Image guided robotic-assisted partial nephrectomy: a multi-institutional propensity score-matched analysis (UroCCR study 51).

Clément Michiels, Zine-Eddine Khene, Thomas Prudhomme, Astrid Boulenger de Hauteclocque, François H Cornelis, Mélanie Percot, Hélène Simeon, Laure Dupitout, Henri Bensadoun, Grégoire Capon and 9 more

2 registry-linked trialsAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03293563 recruitingnot on this map

UroCCR Database: French Research Network for Kidney Cancer (National Multidisciplinary Clinical and Biological Database on Kidney Cancer)

TypeobservationalSponsorUniversity Hospital, BordeauxRan2011 to 2040Enrolled30,000ConditionsKidney CancerArmsRadical nephrectomy versus partial nephrectomy (according surgeon judgement)
NCT05572216 narecruitingnot on this map

A CCafU-UroCCR Randomized Trial: 3D Image-Guided Robot-AssisTEd Partial Nephrectomy for Renal Complex Tumor (UroCCR N°99)

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2023 to 2027Enrolled694ConditionsRenal Tumor, Renal CancerArmsRobot assisted partial nephrectomy with 3D image guidance
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 67 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Clément MichielsDepartment of Urology, Bordeaux University Hospital, Bordeaux, France. clement.michiels@gmail.com.ORCID http://orcid.org/0000-0002-9415-4355
Zine-Eddine KheneDepartment of Urology, Rennes University Hospital, Rennes, France.
Thomas PrudhommeDepartment of Urology, Toulouse University Hospital, Toulouse, France.
Astrid Boulenger de HauteclocqueDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
François H CornelisDepartment of Radiology, Bordeaux University Hospital, Bordeaux, France.
Mélanie PercotDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Hélène SimeonDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Laure DupitoutDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Henri BensadounDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Grégoire CaponDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Eric AlezraDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Vincent EstradeDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Franck BladouDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Grégoire RobertDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Jean-Marie FerriereDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Nicolas GrenierDepartment of Radiology, Bordeaux University Hospital, Bordeaux, France.
Nicolas DoumercDepartment of Urology, Toulouse University Hospital, Toulouse, France.
Karim BensalahDepartment of Urology, Rennes University Hospital, Rennes, France.
Jean-Christophe BernhardDepartment of Urology, Bordeaux University Hospital, Bordeaux, France.
Université de Bordeaux · FRCentre Hospitalier Universitaire de Rennes · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRobot-assisted partial nephrectomy (RAPN) is a difficult procedure with risk of significant perioperative complications. The objective was to evaluate the impact of preoperative planning and intraoperative guidance with 3D model reconstructions on perioperative outcomes of RAPN.

methodsWe conducted a retrospective analysis of all patients who underwent RAPN for kidney tumor by three high-volume expert surgeons from academic centers. Clinical data were collected prospectively after written consent into the French kidney cancer network database UroCCR (CNIL-DR 2013-206; NCT03293563). Our cohort was divided into two groups: 3D-Image guided RAPN group (3D-IGRAPN) and control group. A propensity score according to age, pre-operative renal function and RENAL tumor complexity score was used. Both surgical techniques were compared in terms of perioperative outcomes.

resultsThe initial study cohort included 230 3D-IGRAPN and 415 control RAPN. Before propensity-score matching, patients in the 3D-IGRAPN group had a larger tumor (4.3 cm vs. 3.5 cm, P < 0.001) and higher RENAL complexity score (9 vs. 8, P < 0.001). Following propensity-score matching, there were 157 patients in both groups. The rate of major complications was lower for patients in the 3D-IGRAPN group (3.8% vs. 9.5%, P = 0.04). The median percentage of eGFR variation recorded at first follow-up was lower in the 3D-IGRAPN group (- 5.6% vs. - 10.5%, P = 0.002). The trifecta achievement rate was higher in the 3D-IGRAPN group (55.7% vs. 45.1%; P = 0.005).

conclusionThree-dimensional kidney reconstructions use for pre-operative planning and intraoperative surgical guidance lowers the risk of complications and improve perioperative clinical outcomes of RAPN.

Indexed as

Kidney NeoplasmsRobotic Surgical ProceduresHumansNephrectomyPropensity ScoreRetrospective StudiesTreatment OutcomeImage-guided surgeryPartial nephrectomyRenal cell carcinomaRobotic surgical proceduresThree-dimensional reconstructionTrifecta

Identifiers

PMID33811291
OpenAlexW3147514294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.