Evidence map›Paper›PMID 33811039›Full record

Trial reportThe British journal of ophthalmology2022

One-year myopia control efficacy of spectacle lenses with aspherical lenslets.

Jinhua Bao, Adeline Yang, Yingying Huang, Xue Li, Yiguo Pan, Chenglu Ding, Ee Woon Lim, Jingwei Zheng, Daniel P Spiegel, Björn Drobe and 2 more

9 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The British journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 145 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 7 pooled it
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05288335 naunknown statusnot on this map

Muti-center Clinical Trial to Evaluate the Safety and Efficacy of Two Types of Circular Column Modulated Lenses for Delaying the Progression of Myopia

TypeinterventionalSponsorTianjin Eye HospitalRan2022 to 2024Enrolled240ConditionsMyopiaArmsCircular cylindrical mirror modulated frame glasses (compact), Circular cylindrical mirror modulated frame glasses (strong defocus), single vision frame glasses
NCT05331378 naactive not recruitingnot on this map

A Double-masked, Randomized, 2-armed Comparative Study of a Myopia Control Lens (Test Lens) Versus Single Vision Lens (Control Lens).

TypeinterventionalSponsorEssilor InternationalRan2022 to 2025Enrolled80ConditionsMyopia, Progressive, MyopiaArmsTest myopia control lenses, Single vision lenses
NCT05534022 naactive not recruitingnot on this map

Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression - Open Clinical Trial

TypeinterventionalSponsorEssilor InternationalRan2022 to 2024Enrolled40ConditionsMyopiaArmsTest myopia control lenses (BSL)
NCT05724186 nacompletednot on this mapstarted 2023, after this paper: background citation

Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression - Contiguous Spherical Lenslet

TypeinterventionalSponsorEssilor InternationalRan2023 to 2024Enrolled40ConditionsMyopiaArmsTest myopia control lenses (CSL)
NCT05740930 nacompletednot on this mapstarted 2023, after this paper: background citation

Effectiveness and Safety of Partition Multi-point Defocused Myopia Management Spectacle Lens in Myopia Control Compared With Spectacle Lenses With Aspherical Lenslets: a Randomised Non-inferiority Trial

TypeinterventionalSponsorZhongshan Ophthalmic Center, Sun Yat-sen UniversityRan2023 to 2025Enrolled194ConditionsMyopiaArmsPartition defocus myopia management spectacle lens, Spectacle lenses with aspherical lenslets
NCT05818033 nacompletednot on this mapstarted 2023, after this paper: background citation

Safety and Effectiveness of CARE1.02 Spectacle Lens Versus Single-vision Spectacle Lens in Myopia Control: a Randomised Controlled Trial

TypeinterventionalSponsorZhongshan Ophthalmic Center, Sun Yat-sen UniversityRan2023 to 2025Enrolled796ConditionsMyopiaArmsCARE1.02, Single-vision spectacle lens
NCT05840185 naterminatednot on this mapstarted 2023, after this paper: background citation

Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression - DAL

TypeinterventionalSponsorEssilor InternationalRan2023 to 2024Enrolled41ConditionsMyopiaArmsTest myopia control lenses (DAL)
NCT06263946 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Post Market Clinical Follow-up Study to Demonstrate the Efficacy, Safety, Acceptability and Quality of Life Implications of Essilor® Stellest® Spectacle Lenses in Slowing Myopia Progression in Children and Adolescents.

TypeinterventionalSponsorEssilor InternationalRan2024 to 2027Enrolled150ConditionsMyopiaArmsEssilor® Stellest® spectacle lenses
NCT06857864 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Exploratory Study on the Effectiveness of Myopia Control Lenses in Slowing Myopia Progression in Young Children

TypeinterventionalSponsorEssilor InternationalRan2025 to 2026Enrolled25ConditionsMyopiaArmsTest myopia control lenses (BSL)
3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 7 syntheses or guidelines pooled it, 186 citations in OpenAlex.

  1. Pooled it
  2. [Optimization of Comprehensive Prevention and Control Strategies for Myopia From the Persepctive of the Social Ecological Systems Theory].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Pooled it
  3. Efficacy of spectacle lenses specifically designed for myopia control: systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Pooled it
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. The Impact of Myopia Control Spectacle Lens Designs on Visual Function.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Trial
  13. Trial
  14. Trial
  15. Trial
  16. Clinical evaluation of MyoCare in Europe (CEME) for myopia management: One-year results.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Jinhua Bao *Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Adeline Yang *Wenzhou Medical University-Essilor International Research Center (WEIRC), Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yingying HuangEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID 0000-0001-7694-513X
Xue LiEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yiguo PanEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chenglu DingEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ee Woon LimWenzhou Medical University-Essilor International Research Center (WEIRC), Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jingwei ZhengEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Daniel P SpiegelWenzhou Medical University-Essilor International Research Center (WEIRC), Wenzhou Medical University, Wenzhou, Zhejiang, China.
Björn DrobeWenzhou Medical University-Essilor International Research Center (WEIRC), Wenzhou Medical University, Wenzhou, Zhejiang, China.
Fan LuEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China chenhao@mail.eye.ac.cn Lufan62@mail.eye.ac.cn.ORCID 0000-0002-8794-6944
Hao ChenEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China chenhao@mail.eye.ac.cn Lufan62@mail.eye.ac.cn.ORCID 0000-0002-8594-5630
Essilor (Germany) · DEWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo evaluate the 1-year efficacy of two new myopia control spectacle lenses with lenslets of different asphericity.

methodsOne hundred seventy schoolchildren aged 8-13 years with myopia of -0.75 D to -4.75 D were randomised to receive spectacle lenses with highly aspherical lenslets (HAL), spectacle lenses with slightly aspherical lenslets (SAL), or single-vision spectacle lenses (SVL). Cycloplegic autorefraction (spherical equivalent refraction (SER)), axial length (AL) and best-corrected visual acuity (BCVA) were measured at baseline and 6-month intervals. Adaptation and compliance questionnaires were administered during all visits.

resultsAfter 1 year, the mean changes in the SER (±SE) and AL (±SE) in the SVL group were -0.81±0.06 D and 0.36±0.02 mm. Compared with SVL, the myopia control efficacy measured using SER was 67% (difference of 0.53 D) for HAL and 41% (difference of 0.33 D) for SAL, and the efficacy measured using AL was 64% (difference of 0.23 mm) for HAL and 31% (difference of 0.11 mm) for SAL (all p<0.01). HAL resulted in significantly greater myopia control than SAL for SER (difference of 0.21 D, p<0.001) and AL (difference of 0.12 mm, p<0.001). The mean BCVA (-0.01±0.1 logMAR, p=0.22) and mean daily wearing time (13.2±2.6 hours, p=0.26) were similar among the three groups. All groups adapted to their lenses with no reported adverse events, complaints or discomfort.

conclusionsSpectacle lenses with aspherical lenslets effectively slow myopia progression and axial elongation compared with SVL. Myopia control efficacy increased with lenslet asphericity. TRIAL REGISTRATION NUMBER: ChiCTR1800017683.

Indexed as

EyeglassesMyopiaAdolescentChildDisease ProgressionHumansRefraction, OcularVision Testschild health (paediatrics)clinical trialoptics and refractionvision

Identifiers

PMID33811039
PMCPMC9340037
OpenAlexW3148490085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.