Evidence map›Paper›PMID 33810596›Full record

ReviewGenes2021

Diverse Regulation but Conserved Function: SOX9 in Vertebrate Sex Determination.

Brittany Vining, Zhenhua Ming, Stefan Bagheri-Fam, Vincent Harley

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Differences of sex development.Nature reviews. Disease primers · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Overexpression ofZoological research · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Identification and functional analysis ofFrontiers in genetics · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brittany ViningSex Development Laboratory, Hudson Institute of Medical Research, Melbourne, VIC 3168, Australia.
Zhenhua MingSex Development Laboratory, Hudson Institute of Medical Research, Melbourne, VIC 3168, Australia.
Stefan Bagheri-FamSex Development Laboratory, Hudson Institute of Medical Research, Melbourne, VIC 3168, Australia.
Vincent HarleySex Development Laboratory, Hudson Institute of Medical Research, Melbourne, VIC 3168, Australia.
Hudson Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sex determination occurs early during embryogenesis among vertebrates. It involves the differentiation of the bipotential gonad to ovaries or testes by a fascinating diversity of molecular switches. In most mammals, the switch is

Indexed as

AnimalsFemaleGene Expression Regulation, DevelopmentalMaleSex Determination ProcessesSex DifferentiationSOX9 Transcription FactorVertebratesSOX9 Transcription Factorevolutionsex determinationSOX9transcription factortransdifferentiation

Identifiers

PMID33810596
PMCPMC8066042
OpenAlexW3150227229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.