Evidence map›Paper›PMID 33810534›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Risk Score for Predicting In-Hospital Mortality in COVID-19 (RIM Score).

Alejandro López-Escobar, Rodrigo Madurga, José María Castellano, Sara Velázquez, Rafael Suárez Del Villar, Justo Menéndez, Alejandro Peixoto, Sara Jimeno, Paula Sol Ventura, Santiago Ruiz de Aguiar

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  10. The Role of Hemogram-derived Ratios in COVID-19 Severity Stratification in a Primary Healthcare Facility.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
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  17. Speech as a Biomarker for COVID-19 Detection Using Machine Learning.Computational intelligence and neuroscience · 2022
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  19. Observational
  20. Computational Intelligence-Based Model for Mortality Rate Prediction in COVID-19 Patients.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Alejandro López-EscobarPediatrics Department, HM Hospitales, Fundación de Investigación HM Hospitales, Facultad de Medicina, Universidad CEU San Pablo, 28015 Madrid, Spain.ORCID 0000-0002-9052-1429
Rodrigo MadurgaFundación de Investigación HM Hospitales, Faculty of Experimental Sciences, Universidad Francisco de Vitoria, 28015 Madrid, Spain.ORCID 0000-0002-1381-2599
José María CastellanoCardiology Department, Hospital Universitario HM Montepríncipe, Grupo HM Hospitales, Fundación de Investigación HM Hospitales, Facultad de Medicina, Universidad CEU San Pablo, Centro Nacional de Investigaciones Cardiovasculares, Instituto de Salud Carlos III, 28015 Madrid, Spain.ORCID 0000-0003-3624-1298
Sara VelázquezAnaesthesiology Department, Hospital Universitario HM Sanchinarro, Hospital Universitario Santa Cristina, Fundación de Investigación HM Hospitales, 28015 Madrid, Spain.ORCID 0000-0002-2335-6152
Rafael Suárez Del VillarInternal Medicine Department, Hospital Universitario HM Sanchinarro, Fundación de Investigación HM Hospitales, 28015 Madrid, Spain.
Justo MenéndezEmergency Department, Grupo HM Hospitales, Fundación de Investigación HM Hospitales, Facultad de Medicina, Universidad CEU San Pablo, 28015 Madrid, Spain.
Alejandro PeixotoFacultad de Medicina, Universidad CEU San Pablo, 28015 Madrid, Spain.
Sara JimenoPediatrics Department, Hospital Universitario HM Puerta del Sur, Móstoles, Fundación de Investigación HM Hospitales, Facultad de Medicina, Universidad CEU San Pablo, 28015 Madrid, Spain.
Paula Sol VenturaPediatrics Department Hospital Universitario HM Nens, Fundación de Investigación HM Hospitales, 08009 Barcelona, Spain.ORCID 0000-0002-7981-8491
Santiago Ruiz de AguiarMedical Management, Hospital Universitario HM Puerta del Sur, Móstoles, Fundación de Investigación HM Hospitales, 28015 Madrid, Spain.
Universidad San Pablo CEU · ESHM Hospitales · ESHospital Universitario Santa Cristina · ESUniversidad Francisco de Vitoria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection by SARS-CoV2 has devastating consequences on health care systems. It is a global health priority to identify patients at risk of fatal outcomes. 1955 patients admitted to HM-Hospitales from 1 March to 10 June 2020 due to COVID-19, were were divided into two groups, 1310 belonged to the training cohort and 645 to validation cohort. Four different models were generated to predict in-hospital mortality. Following variables were included: age, sex, oxygen saturation, level of C-reactive-protein, neutrophil-to-platelet-ratio (NPR), neutrophil-to-lymphocyte-ratio (NLR) and the rate of changes of both hemogram ratios (VNLR and VNPR) during the first week after admission. The accuracy of the models in predicting in-hospital mortality were evaluated using the area under the receiver-operator-characteristic curve (AUC). AUC for models including NLR and NPR performed similarly in both cohorts: NLR 0.873 (95% CI: 0.849-0.898), NPR 0.875 (95% CI: 0.851-0.899) in training cohort and NLR 0.856 (95% CI: 0.818-0.895), NPR 0.863 (95% CI: 0.826-0.901) in validation cohort. AUC was 0.885 (95% CI: 0.885-0.919) for VNLR and 0.891 (95% CI: 0.861-0.922) for VNPR in the validation cohort. According to our results, models are useful in predicting in-hospital mortality risk due to COVID-19. The RIM Score proposed is a simple, widely available tool that can help identify patients at risk of fatal outcomes.

Indexed as

COVID-19hemogram-derived-ratiosneutrophil-to-lymphocyte rationeutrophil-to-platelet ratioNLRNPR

Identifiers

PMID33810534
PMCPMC8065669
OpenAlexW3147994544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.