Evidence map›Paper›PMID 33810497›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Nicotinamide Supplementation Improves Oocyte Quality and Offspring Development by Modulating Mitochondrial Function in an Aged

Hyemin Min, Mijin Lee, Kyoung Sang Cho, Hyunjung Jade Lim, Yhong-Hee Shim

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. TheInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. A Brief Review on Caenorhabditis elegans Role in Modelling Neurodegenerative Disease.Central nervous system agents in medicinal chemistry · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. NADTheranostics · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Mitochondria Biology in Reproductive Function.Antioxidants (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Effects of nicotinamide on follicular development and the quality of oocytes.Reproductive biology and endocrinology : RB&E · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyemin MinDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Mijin LeeDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Kyoung Sang ChoDepartment of Biological Sciences, Konkuk University, Seoul 05029, Korea.ORCID 0000-0002-3277-8269
Hyunjung Jade LimDepartment of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.ORCID 0000-0003-2191-666X
Yhong-Hee ShimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.ORCID 0000-0002-8660-4176
Konkuk University · KR

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Konkuk University Premier Research Fund 2020NIH HHS P40 OD010440
6 · The paper itself

Abstract

Aging is associated with a decline in the quality of biological functions. Among the aging processes, reproductive aging is a critical process because of its intergenerational effects. However, the mechanisms underlying reproductive aging remain largely unknown. Female reproductive aging is the primary reason for limited fertility in mammals. Therefore, we attempted to investigate a modulator that can control female reproductive aging using a

Indexed as

antioxidantC. elegansmitochondrial functionnicotinamideoocyte qualityreactive oxygen species (ROS)reproductive aging

Identifiers

PMID33810497
PMCPMC8066965
OpenAlexW3146220358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.