ArticleMolecules (Basel, Switzerland)2021
Characterization of Natural and Alkaline-Oxidized Proanthocyanidins in Plant Extracts by Ultrahigh-Resolution UHPLC-MS/MS.
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 29 citations in OpenAlex.
- Identification and Structural Elucidation of Galloylated B-Type Procyanidins From Rumex obtusifolius L. Using Enzymatic Digestion, Phloroglucinolysis, and High-Resolution Mass Spectrometry.Journal of separation science · 2026Article
- Ethnopharmacology- and Chemotaxonomy-Guided Evaluation ofACS omega · 2026Article
- Comprehensive metabolites characterization of Alpinia katsumadai seeds via a multiplex approach of UHPLC-MS/MS and GC-MS techniques.Scientific reports · 2025Article
- Pine Bark Tannin-Based Resins for Wood Composite Applications.ACS omega · 2025Article
- Selected strains of the Ganoderma lucidum complex from Finnish forests have excellent broadly acting antiviral properties.Scientific reports · 2025Article
- Article
- Comparison of the Stability of a Camu Camu Extract Dried and Encapsulated by Means of High-Throughput Electrospraying Assisted by Pressurized Gas.Foods (Basel, Switzerland) · 2024Article
- Exploring the Interactions between Plant Proanthocyanidins and Thiabendazole: Insights from Isothermal Titration Calorimetry.Molecules (Basel, Switzerland) · 2024Article
- Polyphenols and Phenolic Glucosides in Antibacterial Twig Extracts of Naturally OccurringPharmaceutics · 2024Article
- Synthesis and Isolation of Phenol- and Thiol-Derived Epicatechin Adducts Prepared from Avocado Peel Procyanidins Using Centrifugal Partition Chromatography and the Evaluation of Their Antimicrobial and Antioxidant Activity.Molecules (Basel, Switzerland) · 2024Article
- High intraspecific variability and previous experience affect polyphenol metabolism in polyphagousEcology and evolution · 2024Article
- Affinity of Tannins to Cellulose: A Chromatographic Tool for Revealing Structure-Activity Patterns.Molecules (Basel, Switzerland) · 2023Article
- Dragon's Blood Sap Microencapsulation within Whey Protein Concentrate and Zein Using Electrospraying Assisted by Pressurized Gas Technology.Molecules (Basel, Switzerland) · 2023Article
- Willow (Frontiers in microbiology · 2023Article
- Inspired by nature: Fiber networks functionalized with tannic acid and condensed tannin-rich extracts of Norway spruce bark show antimicrobial efficacy.Frontiers in bioengineering and biotechnology · 2023Article
- Tackling the Future Pandemics: Broad-Spectrum Antiviral Agents (BSAAs) Based on A-Type Proanthocyanidins.Molecules (Basel, Switzerland) · 2022Review
- Identification of Oxindoleacetic Acid Conjugates in Quinoa (Molecules (Basel, Switzerland) · 2022Article
- Mass Spectrometry-Based Applications in Tannin Analytics: From Qualitative and Quantitative Analyses to Biological Activity.Mass spectrometry reviewsReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In this study, we analyzed the proanthocyanidin (PA) composition of 55 plant extracts before and after alkaline oxidation by ultrahigh-resolution UHPLC-MS/MS. We characterized the natural PA structures in detail and studied the sophisticated changes in the modified PA structures and the typical patterns and models of reactions within different PA classes due to the oxidation. The natural PAs were A- and B-type PCs, PDs and PC/PD mixtures. In addition, we detected galloylated PAs. B-type PCs in different plant extracts were rather stable and showed no or minor modification due to the alkaline oxidation. For some samples, we detected the intramolecular reactions of PCs producing A-type ether linkages. A-type PCs were also rather stable with no or minor modification, but in some plants, the formation of additional ether linkages was detected. PAs containing PD units were more reactive. After alkaline oxidation, these PAs or their oxidation products were no longer detected by MS even though a different type and/or delayed PA hump was still detected by UV at 280 nm. Galloylated PAs were rather stable under alkaline oxidation if they were PC-based, but we detected the intramolecular conversion from B-type to A-type. Galloylated PDs were more reactive and reacted similarly to nongalloylated PDs.
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