Evidence map›Paper›PMID 33810302›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

Fermentation Strategies for Production of Pharmaceutical Terpenoids in Engineered Yeast.

Erdem Carsanba, Manuela Pintado, Carla Oliveira

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. The Antiviral Potential ofMolecules (Basel, Switzerland) · 2024
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Plants (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Supercritical COBiotechnology notes (Amsterdam, Netherlands) · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. A 3D printed plastic frame deeply impacts yeast cell growth.Frontiers in bioengineering and biotechnology · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Erdem CarsanbaAmyris BioProducts Portugal, Unipessoal, Lda. Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Manuela PintadoCBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Universidade Católica Portuguesa, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Carla OliveiraCBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Universidade Católica Portuguesa, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Universidade Católica Portuguesa · PT

Funding

Amyris Bio Products Portugal Unipessoal Lda and Escola Superior de Biotecnolo-gia-Universidade Católica Portuguesa through Alchemy project-Capturing high value from industrial fermentation bio products POCI-01-0247-FEDER-027578
6 · The paper itself

Abstract

Terpenoids, also known as isoprenoids, are a broad and diverse class of plant natural products with significant industrial and pharmaceutical importance. Many of these natural products have antitumor, anti-inflammatory, antibacterial, antiviral, and antimalarial effects, support transdermal absorption, prevent and treat cardiovascular diseases, and have hypoglycemic activities. Production of these compounds are generally carried out through extraction from their natural sources or chemical synthesis. However, these processes are generally unsustainable, produce low yield, and result in wasting of substantial resources, most of them limited. Microbial production of terpenoids provides a sustainable and environment-friendly alternative. In recent years, the yeast

Indexed as

fed-batchfermentationpharmaceuticsS. cerevisiaeterpenoids

Identifiers

PMID33810302
PMCPMC8066412
OpenAlexW3142784986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.