Evidence map›Paper›PMID 33810255›Full record

ArticlePolymers2021

Synthetic Biomimetic Polymethacrylates: Promising Platform for the Design of Anti-Cyanobacterial and Anti-Algal Agents.

Přemysl Mikula, Marie Mlnaříková, Enrico T Nadres, Haruko Takahashi, Pavel Babica, Kenichi Kuroda, Luděk Bláha, Iva Sovadinová

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Přemysl MikulaRECETOX, Faculty of Science, Masaryk University, Kamenice 3, CZ-62500 Brno, Czech Republic.ORCID 0000-0002-7380-9244
Marie MlnaříkováRECETOX, Faculty of Science, Masaryk University, Kamenice 3, CZ-62500 Brno, Czech Republic.
Enrico T NadresDepartment of Biologic and Materials Sciences & Prosthodontics, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.
Haruko TakahashiDepartment of Biologic and Materials Sciences & Prosthodontics, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-8607-796X
Pavel BabicaRECETOX, Faculty of Science, Masaryk University, Kamenice 3, CZ-62500 Brno, Czech Republic.ORCID 0000-0001-6399-3554
Kenichi KurodaDepartment of Biologic and Materials Sciences & Prosthodontics, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-2935-8351
Luděk BláhaRECETOX, Faculty of Science, Masaryk University, Kamenice 3, CZ-62500 Brno, Czech Republic.
Iva SovadinováRECETOX, Faculty of Science, Masaryk University, Kamenice 3, CZ-62500 Brno, Czech Republic.ORCID 0000-0003-0627-243X
Masaryk University · CZUniversity of Michigan · US

Funding

CETOCOEN EXCELLENCE Teaming 2 project 857560JSPS Postdoctoral Fellowships for Research Abroad 26-774long-term research development project of Institute of Botany RVO 67985939NSF National Science Foundation for NSF CAREER Award DMR-0845592RECETOX Research Infrastructure LM2018121
6 · The paper itself

Abstract

Extensive, uncontrolled growth of algae and cyanobacteria is an environmental, public health, economic, and technical issue in managing natural and engineered water systems. Synthetic biomimetic polymers have been almost exclusively considered antimicrobial alternatives to conventional antibiotics to treat human bacterial infections. Very little is known about their applicability in an aquatic environment. Here, we introduce synthetic biomimetic polymethacrylates (SBPs) as a cost-effective and chemically facile, flexible platform for designing a new type of agent suitable for controlling and mitigating photosynthetic microorganisms. Since SBPs are cationic and membranolytic in heterotrophic bacteria, we hypothesized they could also interact with negatively charged cyanobacterial or algal cell walls and membranes. We demonstrated that SBPs inhibited the growth of aquatic photosynthetic organisms of concern, i.e., cyanobacteria (

Indexed as

algaeantimicrobialsbiomimetic polymerscyanobacteriapolymethacrylateswater treatment

Identifiers

PMID33810255
PMCPMC8036423
OpenAlexW3139311685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.