Evidence map›Paper›PMID 33810137›Full record

ReviewGenes2021

Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis.

James A Reihill, Lisa E J Douglas, S Lorraine Martin

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. The Effect of CFTR Modulators on Airway Infection in Cystic Fibrosis.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James A ReihillSchool of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.ORCID 0000-0001-8599-5198
Lisa E J DouglasSchool of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
S Lorraine MartinSchool of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.ORCID 0000-0002-1923-0610
Queen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is a life-limiting genetic disorder caused by loss-of-function mutations in the gene which codes for the CF transmembrane conductance regulator (CFTR) Cl

Indexed as

Mucociliary ClearanceCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorHumansLoss of Function MutationRespiratory MucosaCFTR protein, humanCystic Fibrosis Transmembrane Conductance Regulatorairway hydrationbig potassium (BK)cystic fibrosiscystic fibrosis transmembrane conductance regulator (CFTR)epithelial sodium channel (ENaC)ion channeltransmembrane member 16A (TMEM16A)

Identifiers

PMID33810137
PMCPMC8004921
OpenAlexW3138811744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.