Evidence map›Paper›PMID 33810129›Full record

ReviewBiomolecules2021

Antiviral Cyanometabolites-A Review.

Hanna Mazur-Marzec, Marta Cegłowska, Robert Konkel, Krzysztof Pyrć

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hanna Mazur-MarzecDivision of Marine Biotechnology, University of Gdańsk, Marszałka J. Piłsudskiego 46, PL-81-378 Gdynia, Poland.
Marta CegłowskaInstitute of Oceanology, Polish Academy of Science, Powstańców Warszawy 55, PL-81-712 Sopot, Poland.ORCID 0000-0002-6601-5825
Robert KonkelDivision of Marine Biotechnology, University of Gdańsk, Marszałka J. Piłsudskiego 46, PL-81-378 Gdynia, Poland.
Krzysztof PyrćVirogenetics Laboratory of Virology, Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7A, PL-30-387 Krakow, Poland.ORCID 0000-0002-3867-7688
University of Gdańsk · PLInstytut Oceanologii Polskiej Akademii Nauk · PLJagiellonian University · PL

Funding

National Science Centre in Poland NCN2019/33/B/NZ9/02018Statutory Programme of the Institute of Oceanology, PAS II.3
6 · The paper itself

Abstract

Global processes, such as climate change, frequent and distant travelling and population growth, increase the risk of viral infection spread. Unfortunately, the number of effective and accessible medicines for the prevention and treatment of these infections is limited. Therefore, in recent years, efforts have been intensified to develop new antiviral medicines or vaccines. In this review article, the structure and activity of the most promising antiviral cyanobacterial products are presented. The antiviral cyanometabolites are mainly active against the human immunodeficiency virus (HIV) and other enveloped viruses such as herpes simplex virus (HSV), Ebola or the influenza viruses. The majority of the metabolites are classified as lectins, monomeric or dimeric proteins with unique amino acid sequences. They all show activity at the nanomolar range but differ in carbohydrate specificity and recognize a different epitope on high mannose oligosaccharides. The cyanobacterial lectins include cyanovirin-N (CV-N), scytovirin (SVN), microvirin (MVN),

Indexed as

Anti-HIV AgentsAntineoplastic AgentsAntiviral AgentsBacterial ProteinsCarbohydratesCOVID-19 Drug TreatmentCyanobacteriaHIVHIV InfectionsHumansLectinsPolysaccharidesSARS-CoV-2SimplexvirusAnti-HIV AgentsAntineoplastic AgentsAntiviral AgentsBacterial ProteinsCarbohydratescyanovirin NLectinsPolysaccharidesspirulanantiviral metabolitescyanobacterialectinspolysaccharides

Identifiers

PMID33810129
PMCPMC8004682
OpenAlexW3137392353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.