Evidence map›Paper›PMID 33810069›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Diagnostic Performance of (1→3)-β-D-Glucan Alone and in Combination with

Jan Springer, Jürgen Held, Carlo Mengoli, Paul Gerhardt Schlegel, Florian Gamon, Johannes Träger, Oliver Kurzai, Hermann Einsele, Juergen Loeffler, Matthias Eyrich

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05860387 (Early Diagnosis of Invasive Lung Aspergillosis), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05860387 recruitingnot on this mapstarted 2023, after this paper: background citation

Early Diagnosis of Invasive Lung Aspergillosis

TypeobservationalSponsorUniversity Hospital OstravaRan2023 to 2026Enrolled150ConditionsRespiratory Infection, Invasive Pulmonary AspergillosisArmsNext generation improvement of early invasive aspergillosis
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Beta-D-Glucan in Patients with Haematological Malignancies.Journal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jan SpringerDepartment for Internal Medicine II, University Hospital of Würzburg, 97080 Würzburg, Germany.
Jürgen HeldMikrobiologisches Institut-Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany.
Carlo MengoliDepartment of Histology, Microbiology, and Medical Biotechnology, University of Padua, 35122 Padua, Italy.
Paul Gerhardt SchlegelKinderklinik und Poliklinik, University Medical Center Würzburg, 97080 Würzburg, Germany.
Florian GamonDepartment for Internal Medicine II, University Hospital of Würzburg, 97080 Würzburg, Germany.
Johannes TrägerMikrobiologisches Institut-Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany.
Oliver KurzaiNational Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, 07745 Jena, Germany.
Hermann EinseleDepartment for Internal Medicine II, University Hospital of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-7680-0819
Juergen LoefflerDepartment for Internal Medicine II, University Hospital of Würzburg, 97080 Würzburg, Germany.
Matthias EyrichKinderklinik und Poliklinik, University Medical Center Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-8099-5903
Universitätsklinikum Würzburg · DEUniversitäts-Kinderklinik Würzburg · DEUniversitätsklinikum Erlangen · DELeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on biomarker-assisted diagnosis of invasive aspergillosis (IA) in pediatric patients is scarce. Therefore, we conducted a cohort study over two years including 404 serum specimens of 26 pediatric patients after allogeneic hematopoietic stem cell transplantation (alloSCT). Sera were tested prospectively twice weekly for

Indexed as

Aspergillusbeta-D-glucangalactomannanpediatricreal-time PCR

Identifiers

PMID33810069
PMCPMC8004996
OpenAlexW3138990257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.