Evidence map›Paper›PMID 33810056›Full record

ReviewMicromachines2021

Can 3D Printing Bring Droplet Microfluidics to Every Lab?-A Systematic Review.

Nafisat Gyimah, Ott Scheler, Toomas Rang, Tamas Pardy

Abstract readReview
In one paragraph

Review in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nafisat GyimahThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0002-0400-9489
Ott SchelerDepartment of Chemistry and Biotechnology, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0002-8428-1350
Toomas RangThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.
Tamas PardyThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0003-1360-4201

Funding

Eesti Teadusagentuur PRG620Eesti Teadusagentuur PUT1435TTÜ development program 2016-2022 project code 2014-2020.4.01.16-0032
6 · The paper itself

Abstract

In recent years, additive manufacturing has steadily gained attention in both research and industry. Applications range from prototyping to small-scale production, with 3D printing offering reduced logistics overheads, better design flexibility and ease of use compared with traditional fabrication methods. In addition, printer and material costs have also decreased rapidly. These advantages make 3D printing attractive for application in microfluidic chip fabrication. However, 3D printing microfluidics is still a new area. Is the technology mature enough to print complex microchannel geometries, such as droplet microfluidics? Can 3D-printed droplet microfluidic chips be used in biological or chemical applications? Is 3D printing mature enough to be used in every research lab? These are the questions we will seek answers to in our systematic review. We will analyze (1) the key performance metrics of 3D-printed droplet microfluidics and (2) existing biological or chemical application areas. In addition, we evaluate (3) the potential of large-scale application of 3D printing microfluidics. Finally, (4) we discuss how 3D printing and digital design automation could trivialize microfluidic chip fabrication in the long term. Based on our analysis, we can conclude that today, 3D printers could already be used in every research lab. Printing droplet microfluidics is also a possibility, albeit with some challenges discussed in this review.

Indexed as

3D printingautomationlab-on-a-chipmicrofluidicsopen-source hardware

Identifiers

PMID33810056
PMCPMC8004812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.