Evidence map›Paper›PMID 33810002›Full record

ArticleFoods (Basel, Switzerland)2021

In Vitro Bile Salt Hydrolase (BSH) Activity Screening of Different Probiotic Microorganisms.

Jimmy G Hernández-Gómez, Argelia López-Bonilla, Gabriela Trejo-Tapia, Sandra V Ávila-Reyes, Antonio R Jiménez-Aparicio, Humberto Hernández-Sánchez

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 110 citations in OpenAlex.

  1. Human colostrum as a probiotic reservoir: a genomic insights into potential probiotic traits.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  9. Effects and mechanism ofWorld journal of gastroenterology · 2026
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  18. Phenotypic and phylogenetic analyses ofJournal of medical microbiology · 2025
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jimmy G Hernández-GómezDepartamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu 399, UP Adolfo López Mateos, Mexico City CP 07738, Mexico.
Argelia López-BonillaCentro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, Yautepec CP 62731, Mexico.
Gabriela Trejo-TapiaCentro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, Yautepec CP 62731, Mexico.ORCID 0000-0002-7479-9332
Sandra V Ávila-ReyesCentro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, Yautepec CP 62731, Mexico.ORCID 0000-0003-0225-9959
Antonio R Jiménez-AparicioCentro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, Yautepec CP 62731, Mexico.
Humberto Hernández-SánchezDepartamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu 399, UP Adolfo López Mateos, Mexico City CP 07738, Mexico.ORCID 0000-0003-0769-8037
Instituto Politécnico Nacional · MX

Funding

Instituto Politécnico Nacional SIP-20200277
6 · The paper itself

Abstract

Bile salt hydrolase (BSH) activity in probiotic strains is usually correlated with the ability to lower serum cholesterol levels in hypercholesterolemic patients. The objective of this study was the evaluation of BSH in five probiotic strains of lactic acid bacteria (LAB) and a probiotic yeast. The activity was assessed using a qualitative direct plate test and a quantitative high-performance thin- layer chromatography assay. The six strains differed in their BSH substrate preference and activity.

Indexed as

bile salt hydrolasecholesterolLactobacillus plantarumprobioticsSaccharomyces boulardii

Identifiers

PMID33810002
PMCPMC8004636
OpenAlexW3139493838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.